Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 589
interventional 314
Observational 248
Registry 27

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 103
Drug|placebo 55
Other 46
Procedure 24
Device 17
Behavioral 10
Biological 10
Dietary Supplement 9
Diagnostic Test 6
Dietary Supplement|placebo 5
Drug|Other 5
Biological|Other 4
Device|Other 4
Biological|placebo 2
Device|Procedure 2
Drug|Procedure 2
Behavioral|Device 1
Combination Product 1
Combination Product|Drug 1
Device|Drug|Other|Procedure 1
Diagnostic Test|Other 1
Dietary Supplement|Drug|placebo 1
Drug|Other|Procedure 1
Drug|placebo|Procedure 1
Other|Procedure 1
placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 70
China 23
France 21
NA 20
Germany 16
Brazil 10
Thailand 10
Canada 9
Egypt 9
Italy 9
United Kingdom 9
Netherlands 8
Bangladesh 5
Greece 5
India 5
Spain 5
Pakistan 4
Switzerland 4
Taiwan 4
Indonesia 3
Mexico 3
Argentina 2
Belgium 2
Ghana 2
Japan 2
Kenya 2
Korea, Republic of 2
Peru 2
Singapore 2
Turkey 2
Uganda 2
United States|Canada 2
Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|Czech Republic|Denmark|Egypt|Finland|France 1
Australia 1
Australia|Belgium|Canada|Czech Republic|Finland|France|Spain 1
Australia|Belgium|France|Malaysia|New Zealand|Sweden|United Kingdom 1
Austria 1
Austria|Belgium|Poland|Portugal|United States|Argentina|Australia|Brazil|Canada|Chile|Czechia|France|Germany|Hong Kong|Israel|Italy|Japan|Korea, Republic of|Netherlands|South Africa|Spain|Switzerland|Taiwan|United Kingdom 1
Belgium|Greece 1
Belgium|Netherlands 1
Burkina Faso|Gambia 1
Cameroon 1
Colombia 1
Czechia 1
Denmark 1
Denmark|Finland|Iceland|Norway 1
France|Germany 1
Georgia|Kazakhstan|Moldova, Republic of|Ukraine|Uzbekistan 1
Germany|Greece 1
Hungary 1
Iran, Islamic Republic of 1
Ireland 1
Israel 1
Jordan 1
Malawi 1
Norway 1
Russian Federation 1
Saudi Arabia 1
Slovakia 1
South Africa 1
Sweden 1
United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Canada|Croatia|Czechia|Finland|France|Germany|Hungary|India|Israel|Korea, Republic of|Netherlands|New Zealand|Peru|Russian Federation|Serbia|Spain|Taiwan|United Kingdom 1
United States|Australia|Austria|Belgium|Brazil|Canada|Chile|Czech Republic|Denmark|Egypt|Finland|France|Germany|Italy|India|Lebanon|Mexico|Netherlands|New Zealand|Norway|Romania|Russian Federation|Saudi Arabia|Singapore|Slovakia|South Africa|Spain|Sweden|Switzerland|Taiwan|Thailand|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|Czech Republic|Finland|Germany|Israel|Italy|Japan|Netherlands|New Zealand|Puerto Rico|Spain|Sweden|United Kingdom 1
United States|Australia|Chile|France|Germany|Italy|Mexico|Poland|Slovakia|Switzerland|United Kingdom 1
United States|Belgium|Canada|Finland|France|Germany|Puerto Rico|Spain|United Kingdom 1
United States|Belgium|Hungary|Netherlands|Poland 1
United States|Canada|France|Germany|Spain 1
United States|Canada|Malaysia|Thailand 1
United States|France 1
United States|France|Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|Czechia|Estonia|Finland|Germany|Greece|Hong Kong|Hungary|India|Israel|Korea, Republic of|Latvia|Malaysia|Netherlands|New Zealand|Portugal|Puerto Rico|Romania|Russian Federation|Slovenia|South Africa|Spain|Sweden|Taiwan|Thailand|United Kingdom 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 217
2 13
3 13
4 3
5 5
6 4
7 4
8 1
9 1
10 5
11 2
12 5
13 5
15 2
16 2
17 2
18 3
20 1
24 1
26 2
27 1
30 1
31 1
34 2
35 1
42 1
43 1
47 1
50 1
51 1
52 2
62 1
71 1
87 1
93 1
98 1
145 1
161 1
251 1
390 1
426 1

Phase

Phase Study_Count
N/A 132
Phase 3 55
Phase 4 46
Phase 2 41
Phase 1 18
Phase 2/Phase 3 12
Phase 1/Phase 2 8
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 41
2 202
3 25
4 13
5 1
6 4
12 1
NA 27

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 8 5.000 10.00000 10.00 20.000 18.0000 4.0000 7.0000
1st Qu. 56 63.750 26.00000 11.50 39.500 50.0000 104.5000 55.0000
Median 104 132.000 39.00000 21.50 68.500 90.0000 277.0000 102.0000
Mean 104 6739.614 39.83333 85.00 164.575 251.0909 819.3636 408.9111
3rd Qu. 152 415.000 50.00000 62.25 190.000 200.0000 600.0000 231.0000
Max. 200 530000.000 76.00000 466.00 1415.000 1579.0000 12500.0000 4760.0000

Trial Group Type

group_type Group_Count
Experimental 277
Active Comparator 138
Placebo Comparator 104
No Intervention 57
Other 29
NA 27
Sham Comparator 8

Intervention Model

intervention_model Study_Count
Parallel Assignment 237
Single Group Assignment 55
Crossover Assignment 7
Factorial Assignment 7
Sequential Assignment 4
NA 4

Primary Purpose

primary_purpose Study_Count
Treatment 203
Prevention 39
Diagnostic 27
Basic Science 11
Health Services Research 10
Other 6
Screening 6
Supportive Care 6
NA 6

Observational Studies

Studies by Country

Country Study_Count
United States 54
China 27
NA 21
Germany 19
France 15
United Kingdom 11
Taiwan 10
Egypt 8
Italy 8
Israel 5
Sweden 5
Belgium 4
Canada 4
Austria 3
Czechia 3
Greece 3
Switzerland 3
Thailand 3
Turkey 3
Hong Kong 2
India 2
Korea, Republic of 2
Lithuania 2
Netherlands 2
Singapore 2
United States|Canada 2
Argentina 1
Austria|Germany 1
Bangladesh 1
Belgium|Cambodia|Congo, The Democratic Republic of the 1
Belgium|France 1
Belgium|France|Germany|Italy|Netherlands 1
Belgium|France|Spain|Switzerland 1
Canada|New Zealand|United Kingdom 1
Czechia|Italy 1
Denmark 1
Estonia 1
Finland 1
France|Italy|Switzerland|United Kingdom 1
France|Spain 1
Indonesia|Thailand|Vietnam 1
Malaysia 1
Pakistan 1
Slovakia 1
South Africa 1
Suriname 1
United States|Australia|Canada|Colombia|Netherlands 1
United States|Canada|Israel|Singapore|United Kingdom 1
United States|Greece 1
United States|Italy|Netherlands 1
United States|Sweden 1

Sites per Study

Site_count Study_Count
1 188
2 23
3 7
4 3
5 8
6 1
7 5
9 1
13 1
14 2
15 1
16 1
19 1
20 1
21 1
24 1
27 1
52 1
64 1

Enrollment Metrics

Measure Observational
Min 4.000
1st Qu 66.000
Median 186.000
Mean 6339.354
3rd Qu 593.250
Max 1129062.000

Observation Model

observational_model Study_Count
Cohort 153
Case-Only 33
Case-Control 26
Case Control 17
Other 10
NA 5
Ecologic or Community 2
Defined Population 1
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 211
Retrospective 25
Cross-Sectional 6
Other 4
Cross-Sectional, Retrospective/Prospective 1
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
NA 6
China 4
Norway 3
Egypt 2
France 2
Austria|Germany|Hungary 1
Belgium 1
Belgium|Croatia 1
Czechia 1
Denmark 1
Germany 1
Korea, Republic of 1
Spain 1
Thailand 1
United States 1

Sites per Study

Site_count Study_Count
1 21
2 1
3 3
4 1
19 1

Enrollment Metrics

Measure Registries
Min 1.000
1st Qu 58.500
Median 175.000
Mean 1517.185
3rd Qu 571.000
Max 20000.000

Registry Model

observational_model Study_Count
Cohort 13
Case-Control 8
Case-Only 4
Other 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 24
Cross-Sectional 1
Other 1
NA 1

Follow-up

target_duration Study_Count
1 Month 4
1 Year 4
1 Day 3
3 Months 3
2 Months 2
28 Days 2
30 Days 2
12 Months 1
14 Days 1
20 Years 1
4 Weeks 1
5 Weeks 1
7 Days 1
90 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04459572 As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPAR https://ClinicalTrials.gov/show/NCT04459572 Completed Ege University 2019-09-27
NCT02376842 Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert https://ClinicalTrials.gov/show/NCT02376842 Completed Stanford University 2015-03-31
NCT01275638 The Effect of Moderate-Dose Steroid Therapy in Sepsis https://ClinicalTrials.gov/show/NCT01275638 Completed TC Erciyes University 2008-05-31
NCT03403530 Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neonates https://ClinicalTrials.gov/show/NCT03403530 Completed Sir Takhtasinhji General Hospital 2018-06-30
NCT03390374 Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants https://ClinicalTrials.gov/show/NCT03390374 Completed Dr Cipto Mangunkusumo General Hospital 2012-11-30
NCT01988428 Prehospital Antibiotics Against Sepsis Trial https://ClinicalTrials.gov/show/NCT01988428 Completed VU University Medical Center 2017-06-30
NCT02025660 Efficacy of Mw Vaccine in Treatment of Severe Sepsis https://ClinicalTrials.gov/show/NCT02025660 Completed Postgraduate Institute of Medical Education and Research 2014-02-28
NCT03371680 Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU) https://ClinicalTrials.gov/show/NCT03371680 Completed University of Padova 2013-12-31
NCT03371602 Study of the Combined Influence of Sepsis and Mechanical Ventilation on the Human Diaphragm https://ClinicalTrials.gov/show/NCT03371602 Recruiting Hospices Civils de Lyon 2020-06-30
NCT02972827 Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02972827 Recruiting Santa Barbara Cottage Hospital 2020-05-31
NCT03340805 Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study https://ClinicalTrials.gov/show/NCT03340805 Completed Children’s Hospital of Philadelphia 2018-08-31
NCT03334227 High Flow Nasal Cannula in Severe Sepsis https://ClinicalTrials.gov/show/NCT03334227 Recruiting Althaia Xarxa Assistencial Universitària de Manresa 2020-02-28
NCT03332225 A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis https://ClinicalTrials.gov/show/NCT03332225 Active, not recruiting Hellenic Institute for the Study of Sepsis 2019-12-03
NCT03299751 Evaluation of bioMarkErs to Reduce Antibiotics Use in hospitalizeD nEonates https://ClinicalTrials.gov/show/NCT03299751 Recruiting Hospices Civils de Lyon 2020-11-30
NCT03295825 Heparin Binding Protein in Early Sepsis Diagnosis https://ClinicalTrials.gov/show/NCT03295825 Completed Hellenic Institute for the Study of Sepsis 2018-06-30
NCT03295162 Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03295162 Completed Ain Shams University 2017-03-01
NCT03277677 The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients https://ClinicalTrials.gov/show/NCT03277677 Recruiting Chulalongkorn University 2018-07-01
NCT03275090 The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis https://ClinicalTrials.gov/show/NCT03275090 Completed Mansoura University Children Hospital 2017-01-02
NCT03258684 Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT03258684 Completed Zhujiang Hospital 2019-02-02
NCT03248297 Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries https://ClinicalTrials.gov/show/NCT03248297 Recruiting University of Alabama at Birmingham 2020-12-31
NCT03246893 Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients https://ClinicalTrials.gov/show/NCT03246893 Recruiting Mahidol University 2020-04-30
NCT03238742 The Efficacy of Xuebijing Injection on Sepsis https://ClinicalTrials.gov/show/NCT03238742 Recruiting Southeast University, China 2019-12-31
NCT03213990 Beta-Lactam InfusioN Group Study https://ClinicalTrials.gov/show/NCT03213990 Recruiting The George Institute 2022-12-31
NCT03199547 Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death https://ClinicalTrials.gov/show/NCT03199547 Recruiting London School of Hygiene and Tropical Medicine 2020-12-31
NCT03175328 CRRT Timing in Sepsis-associated AKI in ICU https://ClinicalTrials.gov/show/NCT03175328 Recruiting Second Affiliated Hospital of Guangzhou Medical University 2022-02-28
NCT02378545 Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis https://ClinicalTrials.gov/show/NCT02378545 Completed University Hospital Plymouth NHS Trust 2016-10-31
NCT03163095 Closed or Open Abdomen for the Management of Abdominal Sepsis https://ClinicalTrials.gov/show/NCT03163095 Recruiting University of Calgary 2022-07-31
NCT03152474 Adrenal Cortical Function and Vitamin A Deficiency in Sepsis https://ClinicalTrials.gov/show/NCT03152474 Completed Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 2000-01-31
NCT03137446 Restrictive Intravenous Fluids Trial in Sepsis https://ClinicalTrials.gov/show/NCT03137446 Completed Rhode Island Hospital 2018-03-30
NCT03129542 Midodrine Hydrochloride in Early Sepsis https://ClinicalTrials.gov/show/NCT03129542 Recruiting Mayo Clinic 2020-07-31
NCT02336620 Balanced Salt Solution VS. Normal Saline Solution in Septic Shock https://ClinicalTrials.gov/show/NCT02336620 Completed Ramathibodi Hospital 2017-01-30
NCT03078335 Glove-based Care in the NICU to Prevent Late Onset Sepsis https://ClinicalTrials.gov/show/NCT03078335 Completed Hamilton Health Sciences Corporation 2018-06-01
NCT03068741 Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) https://ClinicalTrials.gov/show/NCT03068741 Recruiting Sunnybrook Health Sciences Centre 2024-03-31
NCT03066375 Respiratory Variations For Predicting Fluid Responsiveness 2 https://ClinicalTrials.gov/show/NCT03066375 Completed University Hospital, Lille 2015-05-31
NCT03066362 Respiratory Variations for Predicting Fluid Responsiveness https://ClinicalTrials.gov/show/NCT03066362 Completed University Hospital, Lille 2014-01-31
NCT03048994 Glutamine Supplementation in Critically Ill Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT03048994 Completed Changi General Hospital 2013-06-30
NCT03013322 Anticholium® Per Se https://ClinicalTrials.gov/show/NCT03013322 Completed University Hospital Heidelberg 2017-02-18
NCT02987790 Duration of Antibiotic Therapy in Critically Ill Patients: C-reactive Protein-guided Therapy Versus Best Practice https://ClinicalTrials.gov/show/NCT02987790 Completed Federal University of Minas Gerais 2018-08-31
NCT02163174 Pentoxifylline and Late Onset Sepsis in Preterm Infants https://ClinicalTrials.gov/show/NCT02163174 Completed Mansoura University 2013-02-28
NCT02972983 Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT02972983 Completed McGill University Health Centre/Research Institute of the McGill University Health Centre 2019-07-31
NCT02960854 A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock. https://ClinicalTrials.gov/show/NCT02960854 Completed Bristol-Myers Squibb 2018-01-05
NCT02959229 Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis https://ClinicalTrials.gov/show/NCT02959229 Completed Ain Shams University 2015-12-31
NCT02954926 Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis https://ClinicalTrials.gov/show/NCT02954926 Completed Hormozgan University of Medical Sciences 2016-10-31
NCT02941068 the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations https://ClinicalTrials.gov/show/NCT02941068 Completed Nanjing PLA General Hospital 2016-06-30
NCT02929160 Percutaneous Nephrostomy Versus Stent In Sepsis Trial https://ClinicalTrials.gov/show/NCT02929160 Recruiting The Adelaide and Meath Hospital, incorporating The National Children’s Hospital 2019-12-31
NCT02927054 Effect of Education on Resident Physician Knowledge of Sepsis https://ClinicalTrials.gov/show/NCT02927054 Completed University of Utah 2016-09-30
NCT02883595 Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis https://ClinicalTrials.gov/show/NCT02883595 Completed Sun Yat-sen University 2016-09-30
NCT02898961 Impact of 30 mg/kg Amikacin and 8 mg/kg Gentamicin on Serum Concentrations in Critically Ill Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02898961 Completed Centre Hospitalier Universitaire de Nīmes 2015-02-28
NCT02871544 Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis https://ClinicalTrials.gov/show/NCT02871544 Completed Southeast University, China 2016-02-29
NCT02867267 The Efficacy and Safety of Ta1 for Sepsis https://ClinicalTrials.gov/show/NCT02867267 Recruiting Sun Yat-sen University 2020-12-31
NCT02837731 Fluid Responsiveness Evaluation in Sepsis-associated Hypotension https://ClinicalTrials.gov/show/NCT02837731 Completed Cheetah Medical Inc. 2019-03-31
NCT02820675 Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions https://ClinicalTrials.gov/show/NCT02820675 Recruiting Center for Sepsis Control and Care, Germany 2019-07-31
NCT01525316 Lactoferrin for Prevention of Sepsis in Infants https://ClinicalTrials.gov/show/NCT01525316 Completed Universidad Peruana Cayetano Heredia 2016-10-31
NCT02794025 The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02794025 Completed Fujian Provincial Hospital 2013-01-31
NCT02789995 Dysfunctions of Human Muscle Stem Cells in Sepsis https://ClinicalTrials.gov/show/NCT02789995 Completed Institut Pasteur 2018-06-28
NCT02777606 The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis https://ClinicalTrials.gov/show/NCT02777606 Recruiting Guangdong Provincial Hospital of Traditional Chinese Medicine 2018-10-31
NCT02765191 MR-Evaluation of Renal Function In Septic Patients https://ClinicalTrials.gov/show/NCT02765191 Recruiting Uppsala University 2021-10-31
NCT02747121 Effects of External Inspection on Sepsis Detection and Treatment https://ClinicalTrials.gov/show/NCT02747121 Recruiting Norwegian Board of Health Supervision 2020-12-31
NCT02739373 Pharmacokinetics, Safety, Tolerability and Pharmacodynamics of BMS-986189 in Healthy Subjects https://ClinicalTrials.gov/show/NCT02739373 Completed Bristol-Myers Squibb 2016-12-14
NCT02734550 (1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis https://ClinicalTrials.gov/show/NCT02734550 Completed Center for Sepsis Control and Care, Germany 2019-08-22
NCT02734147 High Dose Intravenous Ascorbic Acid in Severe Sepsis https://ClinicalTrials.gov/show/NCT02734147 Completed Christiana Care Health Services 2017-10-08
NCT02730624 Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02730624 Completed Prince of Songkla University 2016-05-31
NCT02721134 Diagnostic Performance of a New Bio-marker During Bacterial Sepsis https://ClinicalTrials.gov/show/NCT02721134 Recruiting Centre Hospitalier Universitaire de Nice 2018-05-31
NCT02711709 Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty https://ClinicalTrials.gov/show/NCT02711709 Active, not recruiting University of Florida 2020-02-29
NCT02707497 The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia https://ClinicalTrials.gov/show/NCT02707497 Recruiting Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 2021-10-31
NCT02655133 Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients. https://ClinicalTrials.gov/show/NCT02655133 Completed Università Politecnica delle Marche 2018-01-01
NCT02647554 Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China https://ClinicalTrials.gov/show/NCT02647554 Recruiting Peking Union Medical College Hospital 2020-05-31
NCT02640807 A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients https://ClinicalTrials.gov/show/NCT02640807 Completed Revimmune 2018-08-27
NCT02606565 Efficacy of Umbilical Cord Cleansing With a Single Application of 4% Chlorhexidine for the Prevention of Newborn Infections in Uganda: a Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT02606565 Recruiting Makerere University 2020-08-31
NCT02606526 Early Versus Late BCG Vaccination in HIV-1 Exposed Infants in Uganda in Uganda https://ClinicalTrials.gov/show/NCT02606526 Recruiting Makerere University 2023-12-31
NCT03090919 The INFUSE Trial - Intervening With Platelet Transfusions in Sepsis https://ClinicalTrials.gov/show/NCT03090919 Recruiting University of Kentucky 2020-12-31
NCT03389555 Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial https://ClinicalTrials.gov/show/NCT03389555 Recruiting Beth Israel Deaconess Medical Center 2019-12-30
NCT02503761 Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis https://ClinicalTrials.gov/show/NCT02503761 Completed Mansoura University 2015-06-30
NCT02474797 Ultrasound Diaphragmatic Thickening to Monitor Its Dysfunction in Patients With Sepsis https://ClinicalTrials.gov/show/NCT02474797 Completed Groupe Hospitalier Paris Saint Joseph 2019-07-08
NCT02473263 Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock https://ClinicalTrials.gov/show/NCT02473263 Active, not recruiting Assistance Publique - Hôpitaux de Paris 2019-02-09
NCT02467023 Project 4B: Lower Extremity Strength Training in ICU Patients https://ClinicalTrials.gov/show/NCT02467023 Completed University of Florida 2016-07-07
NCT02447042 Minimal Volume for a Fluid Challenge in Septic Patients https://ClinicalTrials.gov/show/NCT02447042 Completed St George’s, University of London 2016-02-29
NCT02413541 The Pilot Study of the Efficacy of Polymyxin-B Hemoperfusion in Critically Ill Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02413541 Completed Chulalongkorn University 2015-12-31
NCT02399397 Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics https://ClinicalTrials.gov/show/NCT02399397 Completed Universidade Estadual Paulista Júlio de Mesquita Filho 2015-12-31
NCT02365272 Pharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency Department https://ClinicalTrials.gov/show/NCT02365272 Completed Universitaire Ziekenhuizen Leuven 2014-12-31
NCT02361528 GM-CSF to Decrease ICU Acquired Infections https://ClinicalTrials.gov/show/NCT02361528 Completed Hospices Civils de Lyon 2018-06-01
NCT02354742 Echo vs. EGDT in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02354742 Completed Intermountain Health Care, Inc. 2017-05-31
NCT02346331 Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya https://ClinicalTrials.gov/show/NCT02346331 Completed Duke University 2016-08-31
NCT02330432 Mycobacterium w in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02330432 Recruiting Postgraduate Institute of Medical Education and Research 2019-01-31
NCT02325258 Assessment of a Proposed Microbiological Alert and Its Impact on a Sepsis Campaign https://ClinicalTrials.gov/show/NCT02325258 Completed Hospital General Universitario Gregorio Marañon 2013-01-31
NCT02295514 Correlation Between PTP1B Expression and Organ Failure During Sepsis https://ClinicalTrials.gov/show/NCT02295514 Completed University Hospital, Rouen 2016-05-31
NCT03385850 The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis https://ClinicalTrials.gov/show/NCT03385850 Completed Nanjing First Hospital, Nanjing Medical University 2018-06-30
NCT02276066 Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS https://ClinicalTrials.gov/show/NCT02276066 Active, not recruiting University of Florida 2019-11-20
NCT02273843 A Trial on Different Dosages of Vitamin D in Preterm Infants With Late-onset Sepsis https://ClinicalTrials.gov/show/NCT02273843 Completed Mansoura University Children Hospital 2015-08-31
NCT02246595 Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction https://ClinicalTrials.gov/show/NCT02246595 Completed InflaRx GmbH 2015-12-31
NCT02213796 Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units https://ClinicalTrials.gov/show/NCT02213796 Completed Prince of Songkla University 2013-12-31
NCT02207114 Using Biomarkers to Optimize Antibiotic Strategies in Sepsis https://ClinicalTrials.gov/show/NCT02207114 Active, not recruiting University of Pennsylvania 2016-12-31
NCT02203019 Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure https://ClinicalTrials.gov/show/NCT02203019 Completed Texas Tech University Health Sciences Center 2016-09-22
NCT03256461 Lactate Clearance Goal-directed Therapy in Sepsis https://ClinicalTrials.gov/show/NCT03256461 Recruiting Nanfang Hospital of Southern Medical University 2020-12-31
NCT02159079 A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study) https://ClinicalTrials.gov/show/NCT02159079 Completed Vanderbilt University Medical Center 2016-02-29
NCT02135770 Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis https://ClinicalTrials.gov/show/NCT02135770 Completed Indonesia University 2014-06-30
NCT02106975 Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury https://ClinicalTrials.gov/show/NCT02106975 Completed Virginia Commonwealth University 2017-11-16
NCT02102087 Study to Evaluate the Effectiveness of the Initial Specimen Diversion Device https://ClinicalTrials.gov/show/NCT02102087 Completed Magnolia Medical Technologies, Inc. 2015-10-31
NCT02085590 Effects of BCG on Immune Response https://ClinicalTrials.gov/show/NCT02085590 Completed Radboud University 2014-10-31
NCT01310790 Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01310790 Completed Chinese Septic Shock Network 2009-10-31
NCT01309321 Perinatal Handwashing Intervention in Bangladesh https://ClinicalTrials.gov/show/NCT01309321 Completed International Centre for Diarrhoeal Disease Research, Bangladesh 2013-07-31
NCT01290003 Role of Antibiotics in Preventing Infection in Babies Born Through Meconium Stained Liquor https://ClinicalTrials.gov/show/NCT01290003 Completed Lady Hardinge Medical College 2011-01-31
NCT01284452 Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01284452 Completed Mahidol University 2014-12-31
NCT01280942 Early Warning System for Clinical Deterioration on General Hospital Wards https://ClinicalTrials.gov/show/NCT01280942 Completed Washington University School of Medicine 2012-05-31
NCT01948063 Ubiquinol (Reduced COQ10) for Patients With Sepsis https://ClinicalTrials.gov/show/NCT01948063 Completed Beth Israel Deaconess Medical Center 2014-04-30
NCT01945983 Early Use of Norepinephrine in Septic Shock Resuscitation https://ClinicalTrials.gov/show/NCT01945983 Completed Mahidol University 2017-08-31
NCT01896544 Cholecalciferol Supplementation for Sepsis in the ICU https://ClinicalTrials.gov/show/NCT01896544 Completed Massachusetts General Hospital 2014-08-31
NCT01893346 Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections https://ClinicalTrials.gov/show/NCT01893346 Completed Pfizer 2014-10-31
NCT01867138 Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin https://ClinicalTrials.gov/show/NCT01867138 Completed Hospital Italiano de Buenos Aires 2010-08-31
NCT01862185 The Effect of Semi-quantitative Procalcitonin Assay to The Adequacy of Empirical Antibiotics and Mortality in Septic Patients https://ClinicalTrials.gov/show/NCT01862185 Completed Indonesia University 2013-04-30
NCT01845766 Effects of Early Exercise Rehabilitation on Long-term Functional Recovery in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT01845766 Completed Yonsei University 2014-11-30
NCT04137276 Effect of Intravenous Vitamin C on SOFA Score Among Septic Patients https://ClinicalTrials.gov/show/NCT04137276 Completed Indonesia University 2019-07-31
NCT01790620 Impact of CVVHD With Adsorption Capacity Membranes in Septic Acute Kidney Injury https://ClinicalTrials.gov/show/NCT01790620 Completed Hospital Universitari de Bellvitge 2017-08-31
NCT01784159 ASpirin for Patients With SEPsis and SeptIc Shock https://ClinicalTrials.gov/show/NCT01784159 Recruiting Federal University of São Paulo 2020-12-31
NCT01775020 Dose-response Study of Arginine Supplementation in Severe Sepsis https://ClinicalTrials.gov/show/NCT01775020 Completed Maastricht University Medical Center 2004-05-31
NCT01760967 Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial https://ClinicalTrials.gov/show/NCT01760967 Completed Wakayama Medical University 2016-01-31
NCT01756755 Endotoxin Adsorber Hemoperfusion and Microcirculation https://ClinicalTrials.gov/show/NCT01756755 Completed National Taiwan University Hospital 2018-08-31
NCT01751945 Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project https://ClinicalTrials.gov/show/NCT01751945 Completed Aga Khan University 2013-12-31
NCT01739933 The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure https://ClinicalTrials.gov/show/NCT01739933 Completed Vanderbilt University Medical Center 2019-07-31
NCT01739361 Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis https://ClinicalTrials.gov/show/NCT01739361 Completed Vanderbilt University Medical Center 2013-12-31
NCT03350113 Hemospec Device for Sepsis Diagnosis https://ClinicalTrials.gov/show/NCT03350113 Completed University of Athens 2018-04-30
NCT01728363 Pharmacokinetics (PK) of Antistaphylococcal Antibiotics in Infants (NICHD-2012-02-Staph Trio) https://ClinicalTrials.gov/show/NCT01728363 Completed Duke University 2015-05-31
NCT01724424 Melatonin in Healthy Volunteers https://ClinicalTrials.gov/show/NCT01724424 Completed University of Aberdeen 2013-05-31
NCT01689441 Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis https://ClinicalTrials.gov/show/NCT01689441 Completed Brigham and Women’s Hospital 2014-02-28
NCT03345992 Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System https://ClinicalTrials.gov/show/NCT03345992 Active, not recruiting Hellenic Institute for the Study of Sepsis 2019-09-03
NCT03434028 Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis https://ClinicalTrials.gov/show/NCT03434028 Recruiting Massachusetts General Hospital 2021-03-31
NCT01649921 The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis https://ClinicalTrials.gov/show/NCT01649921 Completed Radboud University 2016-12-31
NCT01626612 De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis https://ClinicalTrials.gov/show/NCT01626612 Completed Assistance Publique Hopitaux De Marseille 2013-04-30
NCT01598831 Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy https://ClinicalTrials.gov/show/NCT01598831 Completed Asahi Kasei Pharma America Corporation 2018-04-05
NCT01593514 Understanding the Immune Response to Two Different Meningitis Vaccines https://ClinicalTrials.gov/show/NCT01593514 Completed University of Oxford 2013-04-30
NCT01568853 A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis https://ClinicalTrials.gov/show/NCT01568853 Completed Jinling Hospital, China 2012-03-31
NCT01551394 Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis https://ClinicalTrials.gov/show/NCT01551394 Completed PENTA Foundation 2014-12-31
NCT01494675 Procalcitonin as a Tool to Shorten Antibiotic Therapy in the ICU https://ClinicalTrials.gov/show/NCT01494675 Completed Hospital Israelita Albert Einstein 2010-02-28
NCT01484106 Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Severe Sepsis https://ClinicalTrials.gov/show/NCT01484106 Completed Cheetah Medical Inc. 2014-08-31
NCT01453270 Emergency Department Management of Sepsis Patients: A Goal-Oriented Non-Invasive Sepsis Trial https://ClinicalTrials.gov/show/NCT01453270 Completed National University Hospital, Singapore 2014-03-31
NCT01450358 Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. https://ClinicalTrials.gov/show/NCT01450358 Completed Instituto do Coracao 2016-05-31
NCT01449721 Preemptive Resuscitation for Eradication of Septic Shock https://ClinicalTrials.gov/show/NCT01449721 Completed Christiana Care Health Services 2015-01-31
NCT01423968 Effect of Lipopolysaccharide on Skeletal Muscle Functions https://ClinicalTrials.gov/show/NCT01423968 Completed University of Nottingham 2012-12-31
NCT01411670 Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock. https://ClinicalTrials.gov/show/NCT01411670 Completed University of Roma La Sapienza 2015-02-28
NCT01355094 Peritoneal Vacuum Therapy to Reduce Inflammatory Response From Abdominal Sepsis/Injury https://ClinicalTrials.gov/show/NCT01355094 Active, not recruiting University of Calgary 2020-06-30
NCT01352182 Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01352182 Completed Children’s Hospital Medical Center, Cincinnati 2016-05-31
NCT01350765 Naushero Feroze Neonatal Survival Project https://ClinicalTrials.gov/show/NCT01350765 Completed Aga Khan University 2013-01-31
NCT01337934 Lactated Ringer Versus Albumin in Early Sepsis Therapy https://ClinicalTrials.gov/show/NCT01337934 Completed University of Sao Paulo 2016-10-31
NCT01329887 The Effect of Ketanserin on the Microcirculation in Sepsis https://ClinicalTrials.gov/show/NCT01329887 Completed Medical Centre Leeuwarden 2014-05-31
NCT04397640 Myocardial Contrast Echocardiography in Septic Patients https://ClinicalTrials.gov/show/NCT04397640 Recruiting Universitair Ziekenhuis Brussel 2023-12-31
NCT04255979 A Study of HY209 in Healthy Male Volunteers for Sepsis https://ClinicalTrials.gov/show/NCT04255979 Recruiting Shaperon 2020-06-30
NCT04203524 Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients With Sepsis https://ClinicalTrials.gov/show/NCT04203524 Recruiting King Hussein Cancer Center 2021-08-21
NCT04227652 Control of Fever in Septic Patients https://ClinicalTrials.gov/show/NCT04227652 Completed University Hospital Ostrava 2019-02-28
NCT04216459 Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis https://ClinicalTrials.gov/show/NCT04216459 Recruiting Mansoura University 2020-07-31
NCT04197115 Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis https://ClinicalTrials.gov/show/NCT04197115 Recruiting IMSS Hospital General de Zona 11, Piedras Negras 2020-08-30
NCT04178382 Effect of PCR-CRISPR/Cas12a on the Early Anti-infective Schemes in Patients With Open Air Pneumonia https://ClinicalTrials.gov/show/NCT04178382 Recruiting Chinese Medical Association 2020-07-30
NCT04160676 Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis https://ClinicalTrials.gov/show/NCT04160676 Recruiting Tanta University 2020-11-30
NCT04152980 Pentoxifylline Dose Optimization in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT04152980 Recruiting Erasmus Medical Center 2020-12-31
NCT04148989 Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care https://ClinicalTrials.gov/show/NCT04148989 Enrolling by invitation Intermountain Health Care, Inc. 2021-03-31
NCT04134624 EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04134624 Enrolling by invitation HealthPartners Institute 2021-01-31
NCT04130230 Adjuvant Use of Neostigmine in Sepsis and Septic Shock. https://ClinicalTrials.gov/show/NCT04130230 Recruiting Mansoura University 2020-03-31
NCT04111822 Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04111822 Recruiting Institut d’Investigació Biomèdica de Girona Dr. Josep Trueta 2020-10-31
NCT02748382 Fluids in Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02748382 Completed McMaster University 2017-08-19
NCT04094597 Safety and Efficacy of Oral Bovine Lactoferrin https://ClinicalTrials.gov/show/NCT04094597 Completed Cairo University 2018-12-28
NCT04083482 Removal of mtDNA in Plasma by Continous Venovenous Hemofiltration in Sepsis https://ClinicalTrials.gov/show/NCT04083482 Enrolling by invitation First People’s Hospital of Chenzhou 2018-09-20
NCT04078594 Electronic Early Notification of Sepsis in Hospitalized Ward Patients https://ClinicalTrials.gov/show/NCT04078594 Recruiting King Abdullah International Medical Research Center 2021-10-30
NCT04039815 Vitamin C, Vitamin B1 and Steroid in Sepsis https://ClinicalTrials.gov/show/NCT04039815 Enrolling by invitation Far Eastern Memorial Hospital 2020-12-31
NCT04014218 Effect of Inhalation Sedation Compared With Propofol on the Sepsis-related Acute Respiratory Distress Syndrome Course https://ClinicalTrials.gov/show/NCT04014218 Recruiting Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy 2019-09-30
NCT03974386 Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic Shock https://ClinicalTrials.gov/show/NCT03974386 Recruiting National Taiwan University Hospital 2020-09-30
NCT03960203 Effect of a Sepsis Prediction Algorithm on Clinical Outcomes https://ClinicalTrials.gov/show/NCT03960203 Completed Dascena 2018-06-30
NCT03926390 Gut Priming With Oral Bovine Colostrum for Preterm Neonates; Randomized Control Trial https://ClinicalTrials.gov/show/NCT03926390 Completed Ain Shams University 2019-06-15
NCT03925857 Prevention of Sepsis-related Organ Dysfunction With Allocetra-OTS https://ClinicalTrials.gov/show/NCT03925857 Completed Enlivex Therapeutics Ltd. 2019-12-10
NCT03924518 Adjunctive Granisetron Therapy in Patients With Sepsis or Septic Shock https://ClinicalTrials.gov/show/NCT03924518 Recruiting Zhujiang Hospital 2020-12-31
NCT03869073 Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study) https://ClinicalTrials.gov/show/NCT03869073 Recruiting University of British Columbia 2021-02-11
NCT03865602 Improving Morbidity During Post-Acute Care Transitions for Sepsis https://ClinicalTrials.gov/show/NCT03865602 Recruiting Atrium Health 2019-12-31
NCT03847961 Efficacy and Safety Study of CA330 Hemoadsorption Device on IL-6 Removal in Septic Patients https://ClinicalTrials.gov/show/NCT03847961 Recruiting First Affiliated Hospital, Sun Yat-Sen University 2020-02-29
NCT03791866 The Th9/IL-9 and Early Enteral Nutrition in Sepsis https://ClinicalTrials.gov/show/NCT03791866 Recruiting Nanjing First Hospital, Nanjing Medical University 2019-12-31
NCT03788772 Systems Analysis of Antigen Presenting Cells in Human Sepsis https://ClinicalTrials.gov/show/NCT03788772 Recruiting Assistance Publique - Hôpitaux de Paris 2022-07-15
NCT02468310 Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana https://ClinicalTrials.gov/show/NCT02468310 Completed Julius Global Health 2017-02-09
NCT03769844 GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study https://ClinicalTrials.gov/show/NCT03769844 Recruiting Nationwide Children’s Hospital 2021-12-05
NCT03765489 Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT03765489 Completed University of Chile 2018-06-21
NCT03755635 Neonatal Sepsis at Neonatal Intensive Care Units in Ghana https://ClinicalTrials.gov/show/NCT03755635 Recruiting University of Copenhagen 2020-01-01
NCT03730636 Procalcitonin and Duration of AntiBiotherapy In Late Onset Sepsis of Neonate https://ClinicalTrials.gov/show/NCT03730636 Recruiting Assistance Publique - Hôpitaux de Paris 2021-06-30
NCT03764085 Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis. https://ClinicalTrials.gov/show/NCT03764085 Completed Yuria-Pharm 2019-12-11
NCT03714841 C-reactive Protein Information and Blood Cultures for Emergency Department Patients With Sepsis https://ClinicalTrials.gov/show/NCT03714841 Recruiting University of British Columbia 2019-09-15
NCT03754257 Effects of High-frequency Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis https://ClinicalTrials.gov/show/NCT03754257 Recruiting Hospital Sirio-Libanes 2021-04-01
NCT03685214 Comparison of Balanced Crystalloids and Normal Saline in Septic Patients https://ClinicalTrials.gov/show/NCT03685214 Recruiting Zhongnan Hospital 2021-04-30
NCT03683329 Antibiotic De-escalation in Onco-hematology Patients for Sepsis or Septic Shock https://ClinicalTrials.gov/show/NCT03683329 Recruiting Institut Paoli-Calmettes 2020-11-30
NCT03655626 Implementation and Evaluations of Sepsis Watch https://ClinicalTrials.gov/show/NCT03655626 Completed Duke University 2019-07-05
NCT03645668 Efficacy and Pharmacokinetics of Meropenem in Severe Septic Patients https://ClinicalTrials.gov/show/NCT03645668 Completed Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2019-11-14
NCT03333304 A Clinical Trial of Procalcitonin-guided Antimicrobial Therapy in Sepsis https://ClinicalTrials.gov/show/NCT03333304 Completed Hellenic Institute for the Study of Sepsis 2019-01-20
NCT03592277 Vitamin C & Thiamine in Sepsis https://ClinicalTrials.gov/show/NCT03592277 Recruiting Saint Francis Care 2020-06-01
NCT03565159 Pneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors https://ClinicalTrials.gov/show/NCT03565159 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2021-01-31
NCT01434121 Ascorbic Acid (Vitamin C) Infusion in Human Sepsis https://ClinicalTrials.gov/show/NCT01434121 Completed Virginia Commonwealth University 2012-09-30
NCT03517007 The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial https://ClinicalTrials.gov/show/NCT03517007 Recruiting Duke University 2020-05-30
NCT03509350 Vitamin C, Thiamine, and Steroids in Sepsis https://ClinicalTrials.gov/show/NCT03509350 Completed Emory University 2019-08-22
NCT03472170 Clinical Trial for Valuation of the Effectiveness of Lactoferrine in the Prevention of Sepsis in New Premature Born. Bimonitorization of the Antinflammatory Mechanisms, Antioxidants and the Intestinal Microbiote. https://ClinicalTrials.gov/show/NCT03472170 Recruiting Maimónides Biomedical Research Institute of Córdoba 2020-03-01
NCT03454087 Study of Early Enteral Dextrose in Sepsis https://ClinicalTrials.gov/show/NCT03454087 Completed University of Pittsburgh 2020-03-02
NCT03453177 Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis https://ClinicalTrials.gov/show/NCT03453177 Completed Drugs for Neglected Diseases 2019-03-14
NCT03452865 Esomeprazole to Reduce Organ Failure in Sepsis https://ClinicalTrials.gov/show/NCT03452865 Recruiting Università Vita-Salute San Raffaele 2022-03-31
NCT03422159 Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis. https://ClinicalTrials.gov/show/NCT03422159 Completed Community Medical Center, Toms River, NJ 2019-06-05
NCT01264536 Pilot Study: Lactoferrin for Prevention of Neonatal Sepsis https://ClinicalTrials.gov/show/NCT01264536 Completed Universidad Peruana Cayetano Heredia 2011-10-31
NCT01263041 Effect of L-arginine and Glutamine on Preterm https://ClinicalTrials.gov/show/NCT01263041 Completed Ain Shams University 2014-02-28
NCT01251081 Effect of the Intensity of Continuous Renal Replacement Therapy https://ClinicalTrials.gov/show/NCT01251081 Completed Zhejiang University 2009-08-31
NCT01247909 Infant Severe Sepsis and Bacterial Meningitis in Malawi https://ClinicalTrials.gov/show/NCT01247909 Completed University of Malawi College of Medicine 2015-02-28
NCT01247792 End-of-life Decision-making in Patients With Sepsis-related Organ Failure https://ClinicalTrials.gov/show/NCT01247792 Completed Center for Sepsis Control and Care, Germany 2014-09-30
NCT01223690 Clarithromycin as Immunomodulator for the Management of Sepsis https://ClinicalTrials.gov/show/NCT01223690 Completed University of Athens 2010-11-30
NCT01222585 Metronidazole Pharmacokinetics (PK) in Premature Infants https://ClinicalTrials.gov/show/NCT01222585 Completed Duke University 2011-11-30
NCT01187134 Medical Education for Sepsis Source Control and Antibiotics https://ClinicalTrials.gov/show/NCT01187134 Completed Center for Sepsis Control and Care, Germany 2013-06-30
NCT01287507 Lactoferrin Prophylaxis in VLBW and Regulator T-cells https://ClinicalTrials.gov/show/NCT01287507 Completed Ankara University 2011-01-31
NCT01162109 Zinc Therapy in Critical Illness https://ClinicalTrials.gov/show/NCT01162109 Active, not recruiting University of Vermont 2017-09-30
NCT01145560 A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFabâ„¢) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock https://ClinicalTrials.gov/show/NCT01145560 Completed AstraZeneca 2012-05-31
NCT01144624 A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFabâ„¢) in Japanese With Severe Sepsis/Septic Shock https://ClinicalTrials.gov/show/NCT01144624 Completed AstraZeneca 2011-08-31
NCT01140269 Rapid Detection of Staphylococcus Aureus in Burn Patients https://ClinicalTrials.gov/show/NCT01140269 Active, not recruiting American Burn Association 2020-05-31
NCT01139489 Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU’s) https://ClinicalTrials.gov/show/NCT01139489 Completed VU University Medical Center 2014-08-31
NCT00250666 Procalcitonin-Guided Antimicrobial Discontinuation https://ClinicalTrials.gov/show/NCT00250666 Completed University Hospital, Geneva 2007-05-31
NCT01201577 Biological Modulation of Bacterial QSSMs, Innate and Adaptive Immunity by Antibiotics, Probiotics and Prebiotics in Healthy Individuals https://ClinicalTrials.gov/show/NCT01201577 Completed University of Nottingham 2011-05-31
NCT01069146 Mild Therapeutic Hypothermia During Severe Sepsis https://ClinicalTrials.gov/show/NCT01069146 Completed University Hospital, Brest 2005-01-31
NCT01049529 Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients https://ClinicalTrials.gov/show/NCT01049529 Completed Coordinación de Investigación en Salud, Mexico 2011-06-30
NCT01027897 Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients https://ClinicalTrials.gov/show/NCT01027897 Completed Emory University 2011-12-31
NCT01027429 Simplified Antibiotic Therapy for Sepsis in Young Infants https://ClinicalTrials.gov/show/NCT01027429 Completed Aga Khan University 2013-12-31
NCT01013662 Lipid Profile in Patients With Severe Sepsis or Septic Shock Under Strict or Liberal Glycemic Control https://ClinicalTrials.gov/show/NCT01013662 Completed University of Sao Paulo 2007-07-31
NCT00986271 Extravascular Lung Water Index in Severe Sepsis https://ClinicalTrials.gov/show/NCT00986271 Completed Chang Gung Memorial Hospital NA
NCT00962156 Scandinavian Starch for Severe Sepsis/Septic Shock Trial https://ClinicalTrials.gov/show/NCT00962156 Completed Scandinavian Critical Care Trials Group 2012-03-31
NCT00934011 Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections https://ClinicalTrials.gov/show/NCT00934011 Completed Federal University of Minas Gerais 2012-05-31
NCT00926497 Procalcitonin-Guided Decision Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis https://ClinicalTrials.gov/show/NCT00926497 Completed Luzerner Kantonsspital 2006-12-31
NCT00901940 Understanding the Immune Response to Meningitis Vaccines https://ClinicalTrials.gov/show/NCT00901940 Completed University of Oxford 2010-10-31
NCT00879606 Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00879606 Completed Altor BioScience 2012-10-31
NCT00873327 Pharmacokinetics and Safety of Piperacillin-tazobactam in Neonates https://ClinicalTrials.gov/show/NCT00873327 Completed Duke University 2010-07-31
NCT03237728 Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients https://ClinicalTrials.gov/show/NCT03237728 Completed Tianjin Chasesun Pharmaceutical Co., LTD 2019-09-25
NCT02664753 L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury https://ClinicalTrials.gov/show/NCT02664753 Recruiting Centre Hospitalier Universitaire de Nīmes 2021-03-31
NCT02469571 Modulation of Gut Microbiota in Early Sepsis: A Pilot Study https://ClinicalTrials.gov/show/NCT02469571 Completed Medical University of Graz 2016-07-31
NCT00832039 Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis https://ClinicalTrials.gov/show/NCT00832039 Completed Kompetenznetz Sepsis 2013-03-31
NCT00823108 Rapid Administration of Insulin in Sepsis https://ClinicalTrials.gov/show/NCT00823108 Completed Atrium Health 2010-10-31
NCT00844337 Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh https://ClinicalTrials.gov/show/NCT00844337 Completed Johns Hopkins Bloomberg School of Public Health 2013-09-30
NCT03497182 Sepsis, Severe Sepsis and Septic Shock Detection by Breath Analysis https://ClinicalTrials.gov/show/NCT03497182 Completed Landon Pediatric Foundation 2018-10-06
NCT03405870 LIPIDS-P Trial Phase I/II https://ClinicalTrials.gov/show/NCT03405870 Recruiting University of Florida 2021-02-11
NCT03344627 Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients https://ClinicalTrials.gov/show/NCT03344627 Completed Mahidol University 2018-11-30
NCT03019965 Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis https://ClinicalTrials.gov/show/NCT03019965 Completed Coordinación de Investigación en Salud, Mexico 2019-07-30
NCT02899143 Short-course Antimicrobial Therapy in Sepsis https://ClinicalTrials.gov/show/NCT02899143 Recruiting Ospedale Santa Maria delle Croci 2019-12-31
NCT02654561 Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation https://ClinicalTrials.gov/show/NCT02654561 Recruiting China Medical University, China 2021-02-28
NCT01089361 Immunomodulatory Properties of Ketamine in Sepsis https://ClinicalTrials.gov/show/NCT01089361 Completed Beth Israel Deaconess Medical Center 2010-06-30
NCT04280497 Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis https://ClinicalTrials.gov/show/NCT04280497 Recruiting Assistance Publique - Hôpitaux de Paris 2024-10-31
NCT03821038 Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patients https://ClinicalTrials.gov/show/NCT03821038 Recruiting Revimmune 2020-06-30
NCT03306186 Hemospec Device for the Diagnosis of Sepsis https://ClinicalTrials.gov/show/NCT03306186 Completed University of Athens 2017-12-30
NCT01791712 Efficacy of Online Hemodiafiltrationlysis in Cytokine Removal https://ClinicalTrials.gov/show/NCT01791712 Completed Chulalongkorn University 2011-10-31
NCT01474863 Citrulline in Severe Sepsis https://ClinicalTrials.gov/show/NCT01474863 Completed Vanderbilt University Medical Center 2016-03-31
NCT01333982 Neonatal Sepsis, Evaluation, Bangladesh https://ClinicalTrials.gov/show/NCT01333982 Completed International Centre for Diarrhoeal Disease Research, Bangladesh 2013-12-31
NCT03829683 Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis https://ClinicalTrials.gov/show/NCT03829683 Recruiting Virginia Commonwealth University 2021-02-28
NCT03728998 Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis https://ClinicalTrials.gov/show/NCT03728998 Completed Medical Centre Leeuwarden 2019-03-23
NCT00772096 Septic Encephalopathy and Late Cognitive Dysfunction https://ClinicalTrials.gov/show/NCT00772096 Completed University Hospital, Basel, Switzerland 2011-06-30
NCT00732277 Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study https://ClinicalTrials.gov/show/NCT00732277 Completed University Hospital Southampton NHS Foundation Trust 2012-04-30
NCT00711620 Efficacy of Thymosin alpha1 for Severe Sepsis https://ClinicalTrials.gov/show/NCT00711620 Completed Sun Yat-sen University 2010-12-31
NCT00709358 Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections https://ClinicalTrials.gov/show/NCT00709358 Completed Assistance Publique - Hôpitaux de Paris 2010-09-30
NCT00707785 Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis https://ClinicalTrials.gov/show/NCT00707785 Completed Johns Hopkins University 2011-04-30
NCT00707122 Volume Replacement With Albumin in Severe Sepsis https://ClinicalTrials.gov/show/NCT00707122 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2013-04-30
NCT00676897 Statin Therapy in the Treatment of Sepsis https://ClinicalTrials.gov/show/NCT00676897 Completed Beth Israel Deaconess Medical Center 2010-12-31
NCT00670254 Hydrocortisone for Prevention of Septic Shock https://ClinicalTrials.gov/show/NCT00670254 Completed Charite University, Berlin, Germany 2013-08-31
NCT00646399 Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis https://ClinicalTrials.gov/show/NCT00646399 Completed Biosynexus Incorporated 2011-05-31
NCT00634075 Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00634075 Completed Li Shin Hospital 2009-08-31
NCT00630656 Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis https://ClinicalTrials.gov/show/NCT00630656 Completed Agennix 2009-08-31
NCT00629382 Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis https://ClinicalTrials.gov/show/NCT00629382 Completed St. Bortolo Hospital 2008-04-30
NCT00608322 Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis https://ClinicalTrials.gov/show/NCT00608322 Completed National Institute of General Medical Sciences (NIGMS) 2013-04-30
NCT00568737 The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death https://ClinicalTrials.gov/show/NCT00568737 Completed Eli Lilly and Company NA
NCT00559130 Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis https://ClinicalTrials.gov/show/NCT00559130 Completed MedaSorb Technologies, Inc 2011-04-30
NCT00568893 An Open Label Study of Severe Sepsis in Adults https://ClinicalTrials.gov/show/NCT00568893 Completed Eli Lilly and Company NA
NCT00537693 Cytokine Removal by CRRT in Pediatric Sepsis https://ClinicalTrials.gov/show/NCT00537693 Completed Sunnybrook Health Sciences Centre 2010-04-30
NCT00534287 Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00534287 Completed Kompetenznetz Sepsis 2010-04-30
NCT00518596 Prevention of Infection in Indian Neonates - Phase II Probiotics Study https://ClinicalTrials.gov/show/NCT00518596 Completed NICHD Global Network for Women’s and Children’s Health NA
NCT00510835 Protocolized Care for Early Septic Shock https://ClinicalTrials.gov/show/NCT00510835 Completed University of Pittsburgh 2013-07-31
NCT00493415 The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis https://ClinicalTrials.gov/show/NCT00493415 Completed Medical Centre Leeuwarden 2008-07-31
NCT00490477 The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial https://ClinicalTrials.gov/show/NCT00490477 Completed University of Turin, Italy 2007-07-31
NCT00487656 Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation https://ClinicalTrials.gov/show/NCT00487656 Completed Artisan Pharma, Inc. 2010-05-31
NCT00799916 Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis https://ClinicalTrials.gov/show/NCT00799916 Completed Universidad Nacional de La Plata 2009-08-31
NCT00464204 Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00464204 Completed Fresenius Kabi 2010-05-31
NCT00441792 The Effect of Etomidate on Patient Outcomes After Single Bolus Doses https://ClinicalTrials.gov/show/NCT00441792 Completed Advocate Hospital System 2010-12-31
NCT00430859 Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis https://ClinicalTrials.gov/show/NCT00430859 Completed AM-Pharma 2006-03-31
NCT00407823 Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring https://ClinicalTrials.gov/show/NCT00407823 Completed University of Sao Paulo NA
NCT00818597 Extracorporeal Immune Support System (EISS) for the Treatment of Septic Patients https://ClinicalTrials.gov/show/NCT00818597 Completed University of Rostock 2004-04-30
NCT00406198 Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis https://ClinicalTrials.gov/show/NCT00406198 Completed Hopital Lariboisière NA
NCT00397956 To Evaluate the Treatment Effect of an Anti-Infective Agent for Complicated Infections (0826-053) https://ClinicalTrials.gov/show/NCT00397956 Completed Merck Sharp & Dohme Corp. 2005-12-31
NCT00396344 Cortisol Control of Human Inflammatory Responses to Endotoxin https://ClinicalTrials.gov/show/NCT00396344 Completed Dartmouth-Hitchcock Medical Center 2007-11-30
NCT00386425 Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated) https://ClinicalTrials.gov/show/NCT00386425 Completed Eli Lilly and Company 2009-08-31
NCT00372502 Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation https://ClinicalTrials.gov/show/NCT00372502 Completed National Institute of General Medical Sciences (NIGMS) 2008-12-31
NCT00346580 The Effects of HIV Protease Inhibitors in Severe Sepsis https://ClinicalTrials.gov/show/NCT00346580 Completed Mayo Clinic 2005-09-30
NCT00343317 Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women https://ClinicalTrials.gov/show/NCT00343317 Completed University of KwaZulu NA
NCT00334828 ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00334828 Completed Eisai Inc. 2011-01-31
NCT00333593 Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure https://ClinicalTrials.gov/show/NCT00333593 Completed Austin Health NA
NCT00329680 The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis https://ClinicalTrials.gov/show/NCT00329680 Completed Fernandes Tavora Hospital 2008-12-31
NCT00318552 Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients. https://ClinicalTrials.gov/show/NCT00318552 Completed Pfizer 2006-06-30
NCT00284700 Is Helicobacter Pylori Infection a Cause or Treatment Failure of Iron Deficiency Anemia in Children in Bangladesh? https://ClinicalTrials.gov/show/NCT00284700 Completed International Centre for Diarrhoeal Disease Research, Bangladesh NA
NCT00273728 BaSES Trial: Basel Starch Evaluation in Sepsis https://ClinicalTrials.gov/show/NCT00273728 Completed University Hospital, Basel, Switzerland 2010-06-30
NCT00271752 The Procalcitonin and Survival Study https://ClinicalTrials.gov/show/NCT00271752 Completed Danish Procalcitonin Study Group 2009-09-30
NCT00252915 Reconstruction of Monocytic Immunocompetence by Granulocyte-macrophage-colony Stimulating Factor (GM-CSF) in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00252915 Completed Charite University, Berlin, Germany 2007-01-31
NCT00222222 Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis https://ClinicalTrials.gov/show/NCT00222222 Completed Universitätsmedizin Mannheim 2011-12-31
NCT00159952 Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00159952 Completed Policlinico Hospital 2007-03-31
NCT00158769 A Study To Compare The Effects Of The Infusion Of A Sepsis Drug Between Healthy Adults And Adults With Damaged Livers https://ClinicalTrials.gov/show/NCT00158769 Completed GlaxoSmithKline 2005-10-26
NCT00148278 Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock https://ClinicalTrials.gov/show/NCT00148278 Completed University of Versailles 2004-12-31
NCT00146432 Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1) https://ClinicalTrials.gov/show/NCT00146432 Completed Charite University, Berlin, Germany NA
NCT00143611 Efficacy & Safety of Resatorvid in Adults With Severe Sepsis https://ClinicalTrials.gov/show/NCT00143611 Completed Takeda 2007-02-28
NCT00142220 The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients https://ClinicalTrials.gov/show/NCT00142220 Completed University Medicine Greifswald NA
NCT00138112 Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation https://ClinicalTrials.gov/show/NCT00138112 Completed Memorial Sloan Kettering Cancer Center NA
NCT00135473 Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) https://ClinicalTrials.gov/show/NCT00135473 Completed SepNet - Critical Care Trials Group NA
NCT00121394 Chlorhexidine Vaginal and Infant Wash in Pakistan https://ClinicalTrials.gov/show/NCT00121394 Completed NICHD Global Network for Women’s and Children’s Health 2008-06-30
NCT00089986 GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults https://ClinicalTrials.gov/show/NCT00089986 Completed GlaxoSmithKline 2007-04-01
NCT00113191 Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants https://ClinicalTrials.gov/show/NCT00113191 Completed Bristol-Myers Squibb 2006-06-30
NCT00100308 Unfractioned Heparin for Treatment of Sepsis https://ClinicalTrials.gov/show/NCT00100308 Completed Universidad de Antioquia 2007-07-31
NCT00819416 Fluid Resuscitation in Early Septic Shock https://ClinicalTrials.gov/show/NCT00819416 Completed Ottawa Hospital Research Institute 2009-10-31
NCT00067730 A Safety Evaluation of Drotrecogin Alfa (Activated) in Patients With Blood Cancer, Severe Infection Related to Bone Marrow Transplantation https://ClinicalTrials.gov/show/NCT00067730 Completed Eli Lilly and Company NA
NCT00049777 A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa (Activated) https://ClinicalTrials.gov/show/NCT00049777 Completed Eli Lilly and Company NA
NCT00049764 Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis https://ClinicalTrials.gov/show/NCT00049764 Completed Eli Lilly and Company NA
NCT00046072 A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00046072 Completed Eisai Inc. NA
NCT00045760 The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00045760 Completed Eli Lilly and Company NA
NCT00042588 A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis https://ClinicalTrials.gov/show/NCT00042588 Completed ICOS Corporation NA
NCT00034476 A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00034476 Completed Eli Lilly and Company NA
NCT00031512 Pleconaril Enteroviral Sepsis Syndrome https://ClinicalTrials.gov/show/NCT00031512 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2010-09-30
NCT00615017 AZD9773 Dose Escalation Study https://ClinicalTrials.gov/show/NCT00615017 Completed AstraZeneca 2009-07-31
NCT00207844 Selenium, as Sodium Selenite, in the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT00207844 Completed Centre Hospitalier de Meaux NA
NCT00005888 Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants https://ClinicalTrials.gov/show/NCT00005888 Completed National Center for Research Resources (NCRR) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03356249 Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis https://ClinicalTrials.gov/show/NCT03356249 Recruiting University Hospital Heidelberg 2020-12-31
NCT02739152 TRIAGE: TRIage of Sepsis At emerGency dEpartment https://ClinicalTrials.gov/show/NCT02739152 Completed BioMérieux 2018-01-31
NCT04130789 Personalized Swiss Sepsis Study https://ClinicalTrials.gov/show/NCT04130789 Recruiting University Hospital, Basel, Switzerland 2022-06-30
NCT03408600 Physiologic Indicators for Prognosis in Abdominal Sepsis Study https://ClinicalTrials.gov/show/NCT03408600 Completed World Society of Emergency Surgery 2018-05-01
NCT03378258 Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. https://ClinicalTrials.gov/show/NCT03378258 Completed Belfast Health and Social Care Trust 2019-06-30
NCT01556373 Effects of Acute Systemic Inflammation on Arterial Stiffness and Microcirculation. https://ClinicalTrials.gov/show/NCT01556373 Completed Rennes University Hospital 2015-04-16
NCT03734978 Association Between Different Blood Groups and Sepsis in Preterm Infants https://ClinicalTrials.gov/show/NCT03734978 Recruiting Ankara University 2019-02-01
NCT03819192 Predicting EONS in PPROM Patients https://ClinicalTrials.gov/show/NCT03819192 Active, not recruiting Jena University Hospital 2020-03-31
NCT03355833 Comparing Prognostic Performance of SEPSIS 2 and SEPSIS 3 Strategies at the Emergency Service https://ClinicalTrials.gov/show/NCT03355833 Completed Centre Hospitalier Régional Metz-Thionville 2016-08-31
NCT03314831 The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of Sepsis https://ClinicalTrials.gov/show/NCT03314831 Recruiting Charles University, Czech Republic 2019-12-31
NCT03310840 A Study On the Risk of Nosocomial Infection in Mechanically Ventilated Neonate In NICU of Assiut University Children Hospital (Nicu Eta) https://ClinicalTrials.gov/show/NCT03310840 Completed Assiut University 2019-03-30
NCT01932814 Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful? https://ClinicalTrials.gov/show/NCT01932814 Completed Université Victor Segalen Bordeaux 2 2013-08-31
NCT03280576 Validation of Progranulin as a Biomarker for Sepsis https://ClinicalTrials.gov/show/NCT03280576 Completed Ludwig-Maximilians - University of Munich 2019-04-30
NCT03267160 A Study of Exosome Proteomics and Hemodynamics in Sepsis https://ClinicalTrials.gov/show/NCT03267160 Active, not recruiting Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation 2019-12-30
NCT03249597 Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance https://ClinicalTrials.gov/show/NCT03249597 Recruiting Karolinska Institutet 2018-10-31
NCT03249246 Epidemiology of Sepsis in Turkish ICUs. https://ClinicalTrials.gov/show/NCT03249246 Completed Turkish Intensive Care Society 2016-01-28
NCT03231956 CLEAR Sepsis Clinical Study https://ClinicalTrials.gov/show/NCT03231956 Recruiting Edwards Lifesciences 2021-12-31
NCT03226366 Effect of Emergency Department Care Reorganization on Door-to-antibiotic Times for Sepsis (LDS SWARM) https://ClinicalTrials.gov/show/NCT03226366 Completed Intermountain Health Care, Inc. 2017-01-31
NCT03222986 Sepsis-damaged Organs-double-markers Identification of Organ Failure Using Fluorescent Nanoparticle Tracking Analysis https://ClinicalTrials.gov/show/NCT03222986 Recruiting Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation 2018-12-19
NCT03201679 The Association Between Preoperative Sepsis and the Mortality After Hip Fracture Surgery https://ClinicalTrials.gov/show/NCT03201679 Completed Bispebjerg Hospital 2015-01-30
NCT03145428 Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis https://ClinicalTrials.gov/show/NCT03145428 Completed Beckman Coulter, Inc. 2017-12-22
NCT03141112 The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT03141112 Enrolling by invitation University Hospital Olomouc 2018-12-31
NCT03133208 Sepsis Associated Encephalopathy (SAE) Biomarkers https://ClinicalTrials.gov/show/NCT03133208 Recruiting University of Florida 2021-04-18
NCT03131063 Pharmacokinetic Study of Antibiotics in Patients Assisted by Extracorporeal Membrane Oxygenation (PHARMECMO) https://ClinicalTrials.gov/show/NCT03131063 Completed Groupe Hospitalier Pitie-Salpetriere 2015-04-30
NCT03126032 Early Detection of Glycocalyx Damage in Emergency Room Patients https://ClinicalTrials.gov/show/NCT03126032 Completed University Hospital Muenster 2019-12-31
NCT03113721 Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis https://ClinicalTrials.gov/show/NCT03113721 Active, not recruiting Axis Shield Diagnostics Ltd 2018-12-31
NCT03077672 Mitochondrial DNA as a Biomarker of Sepsis Severity https://ClinicalTrials.gov/show/NCT03077672 Recruiting Weill Medical College of Cornell University 2021-12-31
NCT03037281 Release of Nociceptin From Granulocytes in Sepsis https://ClinicalTrials.gov/show/NCT03037281 Completed University of Leicester 2019-06-30
NCT03015584 Systems Biology Approach to Cognitive Impairment After SepsiS https://ClinicalTrials.gov/show/NCT03015584 Completed Intermountain Health Care, Inc. 2017-07-31
NCT03010410 Platelet Immune Responses in Aging and Influenza and Sepsis (INVACS) https://ClinicalTrials.gov/show/NCT03010410 Enrolling by invitation Intermountain Health Care, Inc. 2019-10-31
NCT02988414 Diagnosis of Bacteremia/Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay https://ClinicalTrials.gov/show/NCT02988414 Completed Karius, Inc. 2017-04-30
NCT02973243 The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III https://ClinicalTrials.gov/show/NCT02973243 Completed Philips Healthcare 2017-02-28
NCT02971111 Thromboelastometry in Assessment of Sepsis Coagulopathy https://ClinicalTrials.gov/show/NCT02971111 Completed University Hospital, Motol 2016-10-31
NCT02953002 The Correlation Between The New Sepsis Scores - SOFA, Quick SOFA and Calibrated Automated Thrombogram Values https://ClinicalTrials.gov/show/NCT02953002 Recruiting HaEmek Medical Center, Israel 2019-12-31
NCT02934997 The Role of Dysfunctional HDL in Sepsis https://ClinicalTrials.gov/show/NCT02934997 Completed University of Florida 2019-05-03
NCT02914756 HMGB1 in ICU-survivors https://ClinicalTrials.gov/show/NCT02914756 Completed Karolinska University Hospital 2018-09-30
NCT02887274 Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis https://ClinicalTrials.gov/show/NCT02887274 Recruiting Chang Gung Memorial Hospital 2018-12-31
NCT01392508 IMproved PREdiction of Severe Sepsis in the Emergency Department https://ClinicalTrials.gov/show/NCT01392508 Completed Axis Shield Diagnostics Ltd 2015-09-30
NCT02782013 Study of Progression of Community Acquired Pneumonia in the Hospital https://ClinicalTrials.gov/show/NCT02782013 Recruiting Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe Seps 2019-12-31
NCT02738164 SEPSIS 3 Critera for Risk Stratification in Emergency Patients https://ClinicalTrials.gov/show/NCT02738164 Completed Societe Française de Medecine d’urgence 2016-07-31
NCT02728401 Genotypes and Phenotypes in Pediatric SIRS and Sepsis https://ClinicalTrials.gov/show/NCT02728401 Completed Seattle Children’s Hospital 2017-12-31
NCT02707718 Biomarkers for the Early Identification of Sepsis in the Emergency Department https://ClinicalTrials.gov/show/NCT02707718 Completed Pitié-Salpêtrière Hospital 2018-03-03
NCT02611271 Elimination of Antibiotics During Renal Replacement Therapy and Cytosorb Adsorptive Therapy https://ClinicalTrials.gov/show/NCT02611271 Recruiting Heinrich-Heine University, Duesseldorf 2020-08-31
NCT02589431 Comparison of Total, Salivary and Calculated Free Cortisol Levels in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02589431 Completed TC Erciyes University 2011-06-30
NCT02569086 Piperacillin PK Analysis in Severe Sepsis Patients https://ClinicalTrials.gov/show/NCT02569086 Completed University of Aarhus 2016-06-30
NCT02562261 Platelet REactivity in Sepsis Syndrome (PRESS) https://ClinicalTrials.gov/show/NCT02562261 Completed University Hospital of Patras 2016-06-30
NCT02560402 The Relation Between the Renal Resistive Index and Glomerular Hyper Filtration https://ClinicalTrials.gov/show/NCT02560402 Completed VU University Medical Center 2016-01-31
NCT02544490 Defining Circulating Micro-RNA Biomarkers for the Early Diagnosis and Prognosis of Sepsis https://ClinicalTrials.gov/show/NCT02544490 Completed National University Hospital, Singapore 2018-12-31
NCT02539147 Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02539147 Completed Groupe Hospitalier Paris Saint Joseph 2014-12-31
NCT02533011 Evaluation of the Heparin Binding Protein Levels in Sepsis https://ClinicalTrials.gov/show/NCT02533011 Completed Christiana Care Health Services 2016-12-31
NCT02532959 Diagnostic Breath Analysis Study to Detect Sepsis https://ClinicalTrials.gov/show/NCT02532959 Completed Landon Pediatric Foundation 2015-09-30
NCT02486783 Infection, Sepsis and Meningitis in Surinamese Neonates https://ClinicalTrials.gov/show/NCT02486783 Completed Academic Hospital Paramaribo 2016-08-31
NCT02448472 Epidemiology of Sepsis in China https://ClinicalTrials.gov/show/NCT02448472 Completed Southeast University, China 2015-12-31
NCT02442596 Abdominal SepsiS Study: Epidemiology of Etiology and Outcome https://ClinicalTrials.gov/show/NCT02442596 Completed European Society of Intensive Care Medicine 2017-04-01
NCT02430142 Microcirculatory Oxygen Uptake in Sepsis https://ClinicalTrials.gov/show/NCT02430142 Completed Universitätsmedizin Mannheim 2016-10-31
NCT02410486 Early-Onset Sepsis an NICHD/CDC Surveillance Study https://ClinicalTrials.gov/show/NCT02410486 Completed NICHD Neonatal Research Network 2017-12-31
NCT02393781 Adrenomedullin and Outcome in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02393781 Completed Sphingotec GmbH 2016-05-31
NCT02370186 The Role of Dysfunctional HDL in Severe Sepsis https://ClinicalTrials.gov/show/NCT02370186 Completed University of Florida 2017-03-12
NCT02361970 Study on the Role of Gamma Delta T Cells in Sepsis Immunosuppression and Its Molecular Mechanism https://ClinicalTrials.gov/show/NCT02361970 Completed West China Hospital 2015-05-31
NCT02288715 Relationship of Cerebral Perfusion Pressure Variability to Sepsis-associated Encephalopathy https://ClinicalTrials.gov/show/NCT02288715 Completed West China Hospital 2015-03-31
NCT02281890 Neurodevelopmental Outcomes After Suspected or Proven Sepsis: Secondary Analysis of INIS Trial Database https://ClinicalTrials.gov/show/NCT02281890 Completed University of Edinburgh 2007-09-30
NCT02276417 PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors https://ClinicalTrials.gov/show/NCT02276417 Recruiting University of Florida 2020-07-31
NCT02248896 Antihypertensive Medications and the Risk of Sepsis https://ClinicalTrials.gov/show/NCT02248896 Completed Boehringer Ingelheim 2011-03-31
NCT02198950 Combined Determination of sTREM-1, PCT and CD64 in Diagnosing Sepsis https://ClinicalTrials.gov/show/NCT02198950 Completed Central Hospital, Nancy, France 2011-10-31
NCT02189434 Does Serum Procalcitonin Levels Predict Sepsis in Patients Undergoing Cytoreductive Surgery https://ClinicalTrials.gov/show/NCT02189434 Completed Eastern Regional Medical Center 2016-04-30
NCT02188992 Early PREdiction of Severe Sepsis I (ExPRES-Sepsis I) Study https://ClinicalTrials.gov/show/NCT02188992 Completed University of Edinburgh 2016-01-31
NCT02157259 An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast Asia https://ClinicalTrials.gov/show/NCT02157259 Completed University of Oxford 2016-02-29
NCT02135796 Echocardiography in Septic Shock https://ClinicalTrials.gov/show/NCT02135796 Recruiting Intermountain Health Care, Inc. 2019-12-31
NCT02026856 Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02026856 Completed Pavol Jozef Safarik University 2013-12-31
NCT02120534 Serum CD14 and CD88 Mointoring in ICU https://ClinicalTrials.gov/show/NCT02120534 Completed Tanta University 2014-04-30
NCT02120521 Serum STREM and MNDA Mointoring in ICU https://ClinicalTrials.gov/show/NCT02120521 Completed Tanta University 2014-04-30
NCT01319630 The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients https://ClinicalTrials.gov/show/NCT01319630 Completed Mercy Research 2013-12-31
NCT01996007 Understanding Pneumococcal Carriage and Disease https://ClinicalTrials.gov/show/NCT01996007 Completed University of Oxford 2015-08-31
NCT01995760 The Most Appropriate Parameter Correlates With Clinical Effectiveness of Vancomycin: Trough Drug Concentration or Area Under Curve (AUC)/Minimum Inhibitory Concentration (MIC)? https://ClinicalTrials.gov/show/NCT01995760 Completed National Taiwan University Hospital 2014-06-30
NCT01995448 Prognostic Interest of Leucocyte Immunophenotyping During the Acute Phase of Sepsis https://ClinicalTrials.gov/show/NCT01995448 Completed University Hospital, Limoges 2015-06-30
NCT01976884 Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis https://ClinicalTrials.gov/show/NCT01976884 Completed Changhai Hospital 2013-01-31
NCT03760315 Comparison of mNGS and Culture to Detect Microbe in Critically Infected Patients and Modification to Anti-infection Treatment and Outcome https://ClinicalTrials.gov/show/NCT03760315 Recruiting Southeast University, China 2020-12-01
NCT01964690 Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial? https://ClinicalTrials.gov/show/NCT01964690 Completed Hopital Saint Roch 2014-04-30
NCT01943747 International Multicentre Prevalence Study on Sepsis https://ClinicalTrials.gov/show/NCT01943747 Completed European Society of Intensive Care Medicine 2013-11-30
NCT01928745 Experimental Determination of Atot en Ka in the Critically Ill https://ClinicalTrials.gov/show/NCT01928745 Completed VU University Medical Center 2014-05-31
NCT01919138 Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units https://ClinicalTrials.gov/show/NCT01919138 Completed National Taiwan University Hospital 2013-12-31
NCT01917461 Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections https://ClinicalTrials.gov/show/NCT01917461 Completed MeMed Diagnostics Ltd. 2013-12-31
NCT01891682 Methionine Metabolism in Parenterally Fed Pediatric Sepsis https://ClinicalTrials.gov/show/NCT01891682 Completed The Cleveland Clinic 2016-10-31
NCT01890928 Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis https://ClinicalTrials.gov/show/NCT01890928 Completed The Cleveland Clinic 2013-10-31
NCT01889264 Methionine Metabolism in Enterally Fed Pediatric Sepsis https://ClinicalTrials.gov/show/NCT01889264 Completed The Cleveland Clinic 2016-10-31
NCT01867905 Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01867905 Completed University of British Columbia 2018-09-05
NCT02025699 Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis https://ClinicalTrials.gov/show/NCT02025699 Completed MeMed Diagnostics Ltd. 2016-06-30
NCT01847248 HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis https://ClinicalTrials.gov/show/NCT01847248 Completed Changhai Hospital 2013-03-31
NCT03584594 Presepsin in the Diagnosis of Sepsis in Critically Ill Patients https://ClinicalTrials.gov/show/NCT03584594 Recruiting University Hospital Ostrava 2021-12-31
NCT01746407 Procurement of Human Specimens for the Evaluation of Early Markers of Sepsis https://ClinicalTrials.gov/show/NCT01746407 Completed Abbott Diagnostics Division 2014-08-31
NCT01726595 Ultrasound Measurement of Reactive Hyperemia in Critical Care https://ClinicalTrials.gov/show/NCT01726595 Completed University of Rochester 2019-12-31
NCT01692847 Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related Outcomes https://ClinicalTrials.gov/show/NCT01692847 Completed Philips Healthcare 2016-02-29
NCT01649440 Sepsis Metabolomics https://ClinicalTrials.gov/show/NCT01649440 Completed Chinese PLA General Hospital 2012-03-31
NCT01632059 Examination of ADMA Serum Level and DDAH II https://ClinicalTrials.gov/show/NCT01632059 Completed Universitätsklinikum Hamburg-Eppendorf 2013-03-31
NCT03379402 Sepsis-3 Study in Northeast Thailand https://ClinicalTrials.gov/show/NCT03379402 Recruiting University of Oxford 2020-06-30
NCT01578226 Procalcitonin in Cirrhotic Patients at High Risk for Sepsis https://ClinicalTrials.gov/show/NCT01578226 Completed University of Modena and Reggio Emilia 2010-09-30
NCT00806325 Clinical Factors Associated With the Development of Severe Sepsis in Patients Being Treated for Acute Myeloid Leukemia https://ClinicalTrials.gov/show/NCT00806325 Completed Ohio State University 2010-02-28
NCT01539356 Hepcidin Levels in Preterm Infants https://ClinicalTrials.gov/show/NCT01539356 Completed Meir Medical Center 2013-02-28
NCT01530932 Immune Activation, Hypoxia and Vasoreaction in Sepsis of Pulmonary Versus Abdominal Origin https://ClinicalTrials.gov/show/NCT01530932 Completed Universitätsmedizin Mannheim 2014-04-30
NCT01523717 Procalcitonin Monitoring Sepsis Study https://ClinicalTrials.gov/show/NCT01523717 Completed Brahms AG 2014-03-31
NCT01490424 TREM-1 Gene Polymorphisms https://ClinicalTrials.gov/show/NCT01490424 Completed Chinese PLA General Hospital 2011-10-31
NCT01431326 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care https://ClinicalTrials.gov/show/NCT01431326 Completed Duke University 2019-11-30
NCT01426711 Critical Care Excellence in Sepsis and Trauma https://ClinicalTrials.gov/show/NCT01426711 Completed Medical University of South Carolina 2012-03-31
NCT01410578 The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO https://ClinicalTrials.gov/show/NCT01410578 Completed Chinese PLA General Hospital 2011-03-31
NCT01406951 Diagnostic Value of sTREM-1 and PCT Level as Well as CPIS Score for Ventilator-Associated Pneumonia Among ICU Sepsis Patients https://ClinicalTrials.gov/show/NCT01406951 Completed Chinese PLA General Hospital 2011-03-31
NCT01403935 Sepsis Institutional Registry in Hospital Italiano de Buenos Aires https://ClinicalTrials.gov/show/NCT01403935 Completed Hospital Italiano de Buenos Aires 2014-03-31
NCT01388725 Comparison the Value of Several Biomarkers of Sepsis https://ClinicalTrials.gov/show/NCT01388725 Completed Chinese PLA General Hospital 2011-07-31
NCT01379404 Bioimpedance Analysis in Septic Intensive Care Unit (ICU) Patients https://ClinicalTrials.gov/show/NCT01379404 Completed St. Joseph’s Healthcare Hamilton 2012-04-30
NCT01378169 SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU https://ClinicalTrials.gov/show/NCT01378169 Completed Groupe Hospitalier Paris Saint Joseph 2013-01-01
NCT01363635 Severe Sepsis/Septic Shock on Admission to the General Surgical ICU https://ClinicalTrials.gov/show/NCT01363635 Completed Mahidol University 2019-01-31
NCT01362920 Diagnostic and Prognostic Value of Serial Procalcitonin (PCT) Measurements in Critically Ill Patients https://ClinicalTrials.gov/show/NCT01362920 Completed The Cleveland Clinic 2012-11-30
NCT01362829 Outcome Predictors in Patients With Severe Sepsis and Optimized Central Venous Oxygen Saturation https://ClinicalTrials.gov/show/NCT01362829 Completed National Taiwan University Hospital 2011-05-31
NCT01359891 Clinical Evaluation of Novel Biomarkers in Patients With Septicemia https://ClinicalTrials.gov/show/NCT01359891 Recruiting Medical University of Graz 2020-10-31
NCT01332734 Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis https://ClinicalTrials.gov/show/NCT01332734 Completed Medical Centre Leeuwarden 2010-08-31
NCT01328509 Zinc and Inflammation in Sepsis https://ClinicalTrials.gov/show/NCT01328509 Completed University of Aberdeen 2013-05-31
NCT04427371 The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis https://ClinicalTrials.gov/show/NCT04427371 Recruiting Southeast University, China 2022-12-31
NCT04372472 SQuISH-COVID: A Pilot Study https://ClinicalTrials.gov/show/NCT04372472 Active, not recruiting Cytovale, Inc. 2020-05-29
NCT02217592 Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand https://ClinicalTrials.gov/show/NCT02217592 Completed University of Oxford 2017-02-28
NCT04353388 Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University https://ClinicalTrials.gov/show/NCT04353388 Recruiting Beckman Coulter, Inc. 2020-05-31
NCT04291417 Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W https://ClinicalTrials.gov/show/NCT04291417 Recruiting Beckman Coulter, Inc. 2020-04-30
NCT04289506 Validation of Molecular and Protein Biomarkers in Sepsis https://ClinicalTrials.gov/show/NCT04289506 Recruiting Public Health England 2021-11-30
NCT04214743 Ocular Microvascular Changes in Patients With Sepsis https://ClinicalTrials.gov/show/NCT04214743 Completed Lithuanian University of Health Sciences 2019-08-31
NCT04199962 Genomics in Infection and Sepsis to Predict Organ Dysfunction and Outcomes in Sepsis https://ClinicalTrials.gov/show/NCT04199962 Recruiting Chinese University of Hong Kong 2022-11-11
NCT04192279 Early Lactate Clearance Rate in Sepsis https://ClinicalTrials.gov/show/NCT04192279 Recruiting The Second Hospital of Hebei Medical University 2020-01-31
NCT03377530 Contamination of Bacillus Species Sepsis. https://ClinicalTrials.gov/show/NCT03377530 Completed Centre Hospitalier René Dubos 2016-08-31
NCT04157452 Prediction of Sepsis After Flexible Ureteroscopy https://ClinicalTrials.gov/show/NCT04157452 Completed Tongji Hospital 2019-08-01
NCT04149132 Pulse Photoplethysmography as an Early Tool for the Diagnosis of Sepsis https://ClinicalTrials.gov/show/NCT04149132 Active, not recruiting Hellenic Institute for the Study of Sepsis 2020-05-08
NCT04141410 Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis https://ClinicalTrials.gov/show/NCT04141410 Recruiting Azienda USL Toscana Centro 2020-10-21
NCT04118179 New Strategy to Predict Early Sepsis https://ClinicalTrials.gov/show/NCT04118179 Recruiting University of British Columbia 2020-07-31
NCT04117568 The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients https://ClinicalTrials.gov/show/NCT04117568 Recruiting Göteborg University 2020-12-31
NCT04114214 Objective Sepsis Identification Tool to Study Sepsis Epidemiology https://ClinicalTrials.gov/show/NCT04114214 Completed Chinese University of Hong Kong 2019-10-10
NCT04105699 Evaluation of Immunoassay Measurements of Pancreatic Stone Protein Performed on abioSCOPE® Device With the PSP Assay on ICU Patients at Risk of Sepsis as an Aid in Identifying Sepsis https://ClinicalTrials.gov/show/NCT04105699 Recruiting Abionic SA 2020-07-31
NCT04094818 HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis https://ClinicalTrials.gov/show/NCT04094818 Enrolling by invitation Inflammatix 2021-10-31
NCT04073771 A Multiple Centre, Cohort Study of New CRRT Membranes oXiris for Patients With Septic Shock https://ClinicalTrials.gov/show/NCT04073771 Recruiting Southeast University, China 2020-06-30
NCT04068298 Temperature Gradients for Sepsis Severity and Fluid Resuscitation https://ClinicalTrials.gov/show/NCT04068298 Recruiting Nanfang Hospital of Southern Medical University 2022-09-01
NCT04063332 Functionality of Endogenous Biological Clock in Sepsis https://ClinicalTrials.gov/show/NCT04063332 Recruiting University of Athens 2020-06-30
NCT04055727 Sepsis at Södersjukhuset-Adherence to Treatment Guidelines https://ClinicalTrials.gov/show/NCT04055727 Recruiting Karolinska Institutet 2021-12-01
NCT03244293 Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis https://ClinicalTrials.gov/show/NCT03244293 Recruiting Suez Canal University 2021-01-01
NCT04033653 Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D https://ClinicalTrials.gov/show/NCT04033653 Completed Southeast University, China 2018-08-31
NCT04032938 Multi-omics Study on Gut Microbiota in Critical Ill Patients After Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT04032938 Recruiting Peking Union Medical College Hospital 2019-09-01
NCT04032743 Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis https://ClinicalTrials.gov/show/NCT04032743 Active, not recruiting Rabin Medical Center 2020-07-31
NCT04028102 Ultrasound Optimization of Initial Fluid Challenge in Sepsis https://ClinicalTrials.gov/show/NCT04028102 Recruiting Nantes University Hospital 2020-03-01
NCT03977688 Evaluating a CytoSorb Score in Septic Shock https://ClinicalTrials.gov/show/NCT03977688 Completed Klinikum Emden 2019-05-30
NCT03966664 Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients https://ClinicalTrials.gov/show/NCT03966664 Recruiting Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2021-06-30
NCT03960307 Glycocalyx and Microcirculation in Sepsis https://ClinicalTrials.gov/show/NCT03960307 Completed University Hospital Muenster 2017-09-30
NCT03952390 Effect of Renin-Angiotensin System on Platelet in Patient With Sepsis https://ClinicalTrials.gov/show/NCT03952390 Completed Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2019-12-10
NCT03938220 Electrical Cardiometry Compared to Transthoracic Echocardiography in Fluid Responsiveness in Sepsis https://ClinicalTrials.gov/show/NCT03938220 Recruiting Tanta University 2020-04-01
NCT03932123 Antibiotic Therapy for Early Onset Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03932123 Recruiting Shandong University 2025-10-31
NCT03929159 Correlating MicroRNA Changes With Sepsis Outcomes https://ClinicalTrials.gov/show/NCT03929159 Recruiting M.D. Anderson Cancer Center 2021-09-30
NCT03913403 Study of Treatment’s Echocardiographic Mechanisms https://ClinicalTrials.gov/show/NCT03913403 Recruiting Intermountain Health Care, Inc. 2021-05-01
NCT03884894 Neonatal Sepsis Diagnosis: ; PCR Commercial Technique and Blood Culture https://ClinicalTrials.gov/show/NCT03884894 Completed IRCCS Policlinico S. Matteo 2016-01-31
NCT03884595 Early Identification of Sepsis in Children https://ClinicalTrials.gov/show/NCT03884595 Recruiting Brno University Hospital 2021-12-31
NCT03881566 Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU Patients https://ClinicalTrials.gov/show/NCT03881566 Recruiting Seoul St. Mary’s Hospital 2020-12-31
NCT03847493 Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death https://ClinicalTrials.gov/show/NCT03847493 Recruiting University Hospital Muenster 2020-06-30
NCT03803813 Incidence of Sepsis After Craniocerebral Operation https://ClinicalTrials.gov/show/NCT03803813 Active, not recruiting Beijing Tiantan Hospital 2018-12-31
NCT03802136 Multiple Biomarkers in ICU Sepsis Patients https://ClinicalTrials.gov/show/NCT03802136 Recruiting Zhongnan Hospital 2019-06-30
NCT03799159 Renal Arterial Resistive Index Versus Novel Biomarkers for Early Prediction of Sepsis Associated-acute Kidney Injury https://ClinicalTrials.gov/show/NCT03799159 Recruiting Alexandria University 2020-06-30
NCT03796715 Red Cell Distribution Width Versus Presepsin (Soluble CD14) as a Prognostic Marker in Critically-ill Sepsis Patients https://ClinicalTrials.gov/show/NCT03796715 Completed Ain Shams University 2018-11-20
NCT03782454 Quantification of Bacterial DNA in Sepsis https://ClinicalTrials.gov/show/NCT03782454 Recruiting Region Örebro County 2021-12-31
NCT03744741 HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study https://ClinicalTrials.gov/show/NCT03744741 Completed Inflammatix 2019-11-25
NCT03721302 NeoAMR Observational Study in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03721302 Recruiting Drugs for Neglected Diseases 2019-12-31
NCT02353910 VTE Incidence in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02353910 Completed University of Utah 2014-12-31
NCT03716310 Platelet Reactivity in Septic Shock https://ClinicalTrials.gov/show/NCT03716310 Completed Università degli Studi di Ferrara 2018-05-30
NCT03708796 DIAGNOSis of Infection in Emergency Department https://ClinicalTrials.gov/show/NCT03708796 Completed Association pour la Formation l’Enseignement et la Recherche du Service de l’Accueil des Urgences 2018-04-13
NCT03661450 Evaluation of CDSS in Detection of SIRS and Sepsis in Pediatric Patients https://ClinicalTrials.gov/show/NCT03661450 Completed Hannover Medical School 2019-03-31
NCT03654456 Impact of Sleep Apnea on Sepsis Mortality https://ClinicalTrials.gov/show/NCT03654456 Recruiting Taipei Veterans General Hospital, Taiwan 2019-05-27
NCT03641534 Monitoring of Perfusion in Sepsis and Malaria https://ClinicalTrials.gov/show/NCT03641534 Recruiting University of Oxford 2019-09-30
NCT03623503 Clinical Criteria for a Pathogen in Term Newborn Suspected of Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03623503 Completed Centre Hospitalier Universitaire, Amiens 2017-07-12
NCT03620409 Identification of Cardiovascular and Molecular Prognostic Factors for the Mid- and Long-term Outcome of Sepsis https://ClinicalTrials.gov/show/NCT03620409 Recruiting Jena University Hospital 2020-12-31
NCT03601767 Derivation and Validation of a Prognostic Model for Septic Patients at Hospital Admission https://ClinicalTrials.gov/show/NCT03601767 Recruiting Azienda Ospedaliera San Paolo 2019-01-01
NCT03598127 Vitamin A Status in Critically Ill Children With Sepsis and Its Association With Illness Severity https://ClinicalTrials.gov/show/NCT03598127 Recruiting West China Hospital 2020-04-01
NCT03588325 Evaluation of MDW for Early Detection of Sepsis, Clinical Validity https://ClinicalTrials.gov/show/NCT03588325 Completed Beckman Coulter, Inc. 2019-08-02
NCT03578978 A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu Hospital https://ClinicalTrials.gov/show/NCT03578978 Recruiting Clinical Research Centre, Malaysia 2020-05-31
NCT03540797 Myeloid-derived Suppressor Cells in Sepsis https://ClinicalTrials.gov/show/NCT03540797 Recruiting Chang Gung Memorial Hospital 2023-12-31
NCT03506152 Evaluation of Serum Procalcitonin in Critically Ill Patients With Suspected Sepsis https://ClinicalTrials.gov/show/NCT03506152 Completed Aga Khan University 2015-12-03
NCT02730468 SEP-SEQ Trial - Determining the Etiology of Sepsis Using an Infectious Disease Diagnostic Sequencing Assay https://ClinicalTrials.gov/show/NCT02730468 Completed Karius, Inc. 2017-09-30
NCT03489447 Mortality of Sepsis in Swedish Intensive Care Units 2008-2016 https://ClinicalTrials.gov/show/NCT03489447 Completed Uppsala University 2017-10-25
NCT03474809 Early Diagnostic of Sepsis and Potential Impact on Antibiotic Management Based on Serial.Pancreatic Stone Protein (PSP) Measured Using the AbioScope. https://ClinicalTrials.gov/show/NCT03474809 Completed Abionic SA 2019-03-15
NCT03433846 Predictors of Sepsis in Ex-Preterm Infants https://ClinicalTrials.gov/show/NCT03433846 Recruiting Boston Children’s Hospital 2020-04-01
NCT01208077 PREMIUM Registry: PRognostic HEModynamIc Profiling in the AcUtely Ill EMergency Department Patient https://ClinicalTrials.gov/show/NCT01208077 Completed Henry Ford Health System 2012-09-30
NCT01236703 Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU https://ClinicalTrials.gov/show/NCT01236703 Completed Charite University, Berlin, Germany 2010-05-31
NCT01161745 PD-1/PD-L1 Pathway Study on Septic Patients https://ClinicalTrials.gov/show/NCT01161745 Completed Changhai Hospital 2010-02-28
NCT01155830 Inflammatory Cytokine Quantification in Infants https://ClinicalTrials.gov/show/NCT01155830 Completed University of Utah 2013-05-31
NCT01128283 Indicators of Inflammation and Coagulation in Sepsis https://ClinicalTrials.gov/show/NCT01128283 Completed University of Oklahoma 2014-05-31
NCT01120678 Improved Detection of Neonatal Sepsis Using a Targeted Biomarker Assay https://ClinicalTrials.gov/show/NCT01120678 Completed University of Virginia 2010-07-31
NCT01099813 Sepsis Pathophysiological & Organisational Timing https://ClinicalTrials.gov/show/NCT01099813 Completed Intensive Care National Audit & Research Centre 2012-12-31
NCT01029080 Cerebrovascular Autoregulation During Sepsis https://ClinicalTrials.gov/show/NCT01029080 Completed Johannes Gutenberg University Mainz 2010-12-31
NCT01012115 Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis https://ClinicalTrials.gov/show/NCT01012115 Completed University of Oklahoma 2011-09-30
NCT02021552 Genetic Polymorphisms & The Risk for Sepsis After Trauma https://ClinicalTrials.gov/show/NCT02021552 Completed University of Washington 2014-12-31
NCT00883597 Sidestream Dark-Field (SDF) Imaging of the Intestinal Microcirculation https://ClinicalTrials.gov/show/NCT00883597 Active, not recruiting Nova Scotia Health Authority 2020-12-31
NCT00874367 Early-Onset Sepsis Surveillance Study https://ClinicalTrials.gov/show/NCT00874367 Completed NICHD Neonatal Research Network 2009-12-31
NCT00866567 Defects in Opsonophagocytosis in Premature Infants https://ClinicalTrials.gov/show/NCT00866567 Completed University Hospital, Geneva 2009-09-30
NCT00862290 Circulating microRNAs as Biomarkers of Sepsis https://ClinicalTrials.gov/show/NCT00862290 Completed Changhai Hospital 2009-04-30
NCT03870789 Field Paramedic Application of Sepsis Triage https://ClinicalTrials.gov/show/NCT03870789 Recruiting Hamilton Health Sciences Corporation 2019-05-01
NCT03780712 Immune Dysfunction in Newborn Sepsis https://ClinicalTrials.gov/show/NCT03780712 Completed BioMérieux 2018-03-12
NCT01968746 The AVERT Sepsis Investigation https://ClinicalTrials.gov/show/NCT01968746 Completed Christiana Care Health Services 2015-01-31
NCT00835913 Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact https://ClinicalTrials.gov/show/NCT00835913 Completed University Hospital, Grenoble 2011-09-30
NCT04322942 Sepsis Prediction by Monocyte Distribution Width and Procalcitonin https://ClinicalTrials.gov/show/NCT04322942 Recruiting Chang Gung Memorial Hospital 2020-09-30
NCT03727243 Molecular Diagnosis and Risk Stratification of Sepsis in India https://ClinicalTrials.gov/show/NCT03727243 Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2020-07-31
NCT03094299 Diaphragm Ultrasound in Weaning From Mechanical Ventilation https://ClinicalTrials.gov/show/NCT03094299 Completed Cairo University 2018-03-21
NCT02755025 Clinical Score Usefulness and EHR Integration https://ClinicalTrials.gov/show/NCT02755025 Completed Mayo Clinic 2016-08-31
NCT02689193 IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres https://ClinicalTrials.gov/show/NCT02689193 Completed Institute of Tropical Medicine, Belgium 2019-08-31
NCT01333657 The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries https://ClinicalTrials.gov/show/NCT01333657 Completed Chinese PLA General Hospital 2011-04-30
NCT00811629 Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients https://ClinicalTrials.gov/show/NCT00811629 Completed University Hospital, Clermont-Ferrand 2009-07-31
NCT01530854 Plasma Free Fatty Acids in Risk Assessment of Sepsis in the Emergency Department: A Prospective Pilot Study https://ClinicalTrials.gov/show/NCT01530854 Completed The Cleveland Clinic 2012-01-31
NCT01362504 Pro-adrenomedullin as a Prognostic Marker in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT01362504 Completed Zekai Tahir Burak Women’s Health Research and Education Hospital 2011-08-31
NCT04026035 PCR Technic Evaluation in the Microbial Diagnostic of Septicemia in Hemodialysis Patients With Catheter. https://ClinicalTrials.gov/show/NCT04026035 Completed University Hospital, Bordeaux 2020-03-05
NCT02883218 Dynamic Alterations of Th2/Th1 With New Onset of Community-acquired Severe Sepsis Patients https://ClinicalTrials.gov/show/NCT02883218 Completed Southeast University, China 2018-07-20
NCT02444871 IgM-enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis https://ClinicalTrials.gov/show/NCT02444871 Completed Goethe University 2013-07-31
NCT02208817 The Paediatric Refill Study (PRefill) https://ClinicalTrials.gov/show/NCT02208817 Completed University of Nottingham 2016-03-31
NCT02189096 Validation of Early Warning Score & Lactate in Prehospital Screening https://ClinicalTrials.gov/show/NCT02189096 Completed University of the West of Scotland 2015-07-31
NCT02170233 SHOCK US STUDY: Fluid Responsiveness in Sepsis Measured by Ultrasonography https://ClinicalTrials.gov/show/NCT02170233 Completed Yale University 2016-06-30
NCT02052895 Utility of Presepsin in Distinguishing Between Sepsis and SIRS https://ClinicalTrials.gov/show/NCT02052895 Completed Mochida Pharmaceutical Company, Ltd. 2015-07-31
NCT01929772 German Lactat Clearance in Severe Sepsis https://ClinicalTrials.gov/show/NCT01929772 Completed RWTH Aachen University 2015-04-30
NCT01806428 Activated Protein C and Microcirculation https://ClinicalTrials.gov/show/NCT01806428 Completed Università Politecnica delle Marche 2010-12-31
NCT01725061 Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis https://ClinicalTrials.gov/show/NCT01725061 Completed Emory University 2012-09-30
NCT01670383 Repository for Sepsis and Postresuscitation Samples https://ClinicalTrials.gov/show/NCT01670383 Recruiting Seoul National University Hospital 2020-12-31
NCT04441944 TELEmedicine as an Intervention for Sepsis in Emergency Departments https://ClinicalTrials.gov/show/NCT04441944 Recruiting University of Iowa 2019-06-30
NCT04439617 Monitoring of the Mitochondrial Function of Circulating Myeloid Cells in Patients Hospitalized in the Intensive Care Unit of Dijon University Hospital https://ClinicalTrials.gov/show/NCT04439617 Completed Centre Hospitalier Universitaire Dijon 2020-01-30
NCT03996759 Early Prediction of Sepsis by Using Metabolomics https://ClinicalTrials.gov/show/NCT03996759 Recruiting Southwest Hospital, China 2021-06-18
NCT03953404 POC SPLA2-IIA as a Biomarker for Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT03953404 Recruiting St. Luke’s Hospital, Pennsylvania 2020-04-30
NCT03777670 nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis https://ClinicalTrials.gov/show/NCT03777670 Recruiting Cardiff and Vale University Health Board 2023-02-28
NCT03682003 Hepcidin: a Prognostic Marker of Morbidity and Mortality in Severe Sepsis? https://ClinicalTrials.gov/show/NCT03682003 Active, not recruiting Rennes University Hospital 2017-07-12
NCT02143986 Glycosylated Ferritin in Macrophagic Activation Syndromes https://ClinicalTrials.gov/show/NCT02143986 Recruiting Brugmann University Hospital 2020-12-31
NCT04049565 CRP Versus PCT as Bio-markers for Sepsis and in Guiding Antibiotics in Critically Ill Patients https://ClinicalTrials.gov/show/NCT04049565 Completed Beni-Suef University 2019-02-01
NCT00793442 Endothelium in Severe Sepsis https://ClinicalTrials.gov/show/NCT00793442 Completed Beth Israel Deaconess Medical Center 2013-05-31
NCT00736827 BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients https://ClinicalTrials.gov/show/NCT00736827 Completed University of Ulm 2012-08-31
NCT00736723 NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock https://ClinicalTrials.gov/show/NCT00736723 Completed University of Ulm 2012-08-31
NCT00716781 Management of Infants Born to Group B Streptococcus Positive Mothers. https://ClinicalTrials.gov/show/NCT00716781 Completed IRCCS Burlo Garofolo 2006-06-30
NCT00698048 Serial Vasopressin and Copeptin Levels in Children With Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00698048 Completed KK Women’s and Children’s Hospital 2011-12-31
NCT00615862 Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis https://ClinicalTrials.gov/show/NCT00615862 Completed Virginia Commonwealth University 2009-05-31
NCT00599794 A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status https://ClinicalTrials.gov/show/NCT00599794 Completed Mayo Clinic 2007-10-31
NCT00591955 Infected Elders in the Emergency Department: Outcomes and Processes of Care https://ClinicalTrials.gov/show/NCT00591955 Completed Ohio State University 2008-10-31
NCT00561639 Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-hematology Patients Presenting Sepsis https://ClinicalTrials.gov/show/NCT00561639 Completed University Hospital, Grenoble NA
NCT00541827 Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis https://ClinicalTrials.gov/show/NCT00541827 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2011-08-31
NCT00518609 Prevention of Infection in Indian Neonates - Phase I Observational Study https://ClinicalTrials.gov/show/NCT00518609 Completed NICHD Global Network for Women’s and Children’s Health NA
NCT00487019 Management of Early Onset Neonatal Septicaemia: Selection of Optimal Antibacterial Regimen for Empiric Treatment https://ClinicalTrials.gov/show/NCT00487019 Completed University of Tartu NA
NCT00488917 Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study) https://ClinicalTrials.gov/show/NCT00488917 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2009-08-31
NCT00463645 Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients https://ClinicalTrials.gov/show/NCT00463645 Completed Medical University of Graz NA
NCT00448968 The Utility of Ischemia Modified Albumin (IMA) in Sepsis https://ClinicalTrials.gov/show/NCT00448968 Completed Inverness Medical Innovations NA
NCT00398736 A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients. https://ClinicalTrials.gov/show/NCT00398736 Completed Charite University, Berlin, Germany NA
NCT00360048 Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy Volunteers https://ClinicalTrials.gov/show/NCT00360048 Completed Medical University of Vienna NA
NCT00229034 Effect of APC and Epo on the Inflammatory Response During Sepsis https://ClinicalTrials.gov/show/NCT00229034 Completed Lawson Health Research Institute 2010-12-31
NCT00185783 Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00185783 Completed Stanford University 2006-11-30
NCT00175526 Predicting Complications in Women With Toxaemia https://ClinicalTrials.gov/show/NCT00175526 Completed University of British Columbia 2010-12-31
NCT00141973 Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment With Corticosteroids https://ClinicalTrials.gov/show/NCT00141973 Completed Ospedale Regionale Bellinzona e Valli NA
NCT00825357 Biological Markers to Identify Early Sepsis and Acute Lung Injury https://ClinicalTrials.gov/show/NCT00825357 Completed Chimei Medical Center 2011-08-31
NCT00781040 Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients https://ClinicalTrials.gov/show/NCT00781040 Completed Kuopio University Hospital 2019-01-01

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03158493 Assessment of qSOFA in the Latin America Sepsis Institute Database https://ClinicalTrials.gov/show/NCT03158493 Completed Federal University of São Paulo 2017-03-31
NCT03025802 Fast Assay for Pathogen Identification and Characterization - Prospective Study https://ClinicalTrials.gov/show/NCT03025802 Completed Hasselt University 2017-06-30
NCT02605681 Midkine and ACE-Ang II Induced Endothelial Injury in Sepsis https://ClinicalTrials.gov/show/NCT02605681 Completed Southeast University, China 2018-03-31
NCT02034240 Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis? https://ClinicalTrials.gov/show/NCT02034240 Completed Sygehus Lillebaelt 2015-04-30
NCT02238795 Sepsis-Associated Purpura Fulminans International Registry - Europe https://ClinicalTrials.gov/show/NCT02238795 Recruiting Jena University Hospital 2019-12-31
NCT02020174 The Preeclampsia Registry https://ClinicalTrials.gov/show/NCT02020174 Recruiting Preeclampsia Foundation 2030-05-31
NCT01947127 Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department https://ClinicalTrials.gov/show/NCT01947127 Completed Chulalongkorn University 2014-11-30
NCT01784458 Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT01784458 Completed University of Ulsan 2009-10-31
NCT03992794 Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department https://ClinicalTrials.gov/show/NCT03992794 Completed Sociedad Española de Medicica de Emergencias 2018-08-31
NCT04292431 Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP) https://ClinicalTrials.gov/show/NCT04292431 Recruiting Beckman Coulter, Inc. 2020-06-30
NCT04226430 Effect of Cytosorb on Blood Levels of Inflammatory Biomarkers of Sepsis. https://ClinicalTrials.gov/show/NCT04226430 Completed University of Gaziantep 2017-06-30
NCT04203979 Sepsis: From Syndrome to Personalized Care https://ClinicalTrials.gov/show/NCT04203979 Recruiting Oslo University Hospital 2020-12-31
NCT04135274 Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Neural Tube Defects? https://ClinicalTrials.gov/show/NCT04135274 Completed Tepecik Training and Research Hospital 2018-12-30
NCT03996720 Early Identification and Effective Management of Pediatric Sepsis https://ClinicalTrials.gov/show/NCT03996720 Recruiting Children’s Hospital of Fudan University 2020-12-31
NCT03943719 Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia https://ClinicalTrials.gov/show/NCT03943719 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2017-12-31
NCT03923543 Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03923543 Completed Tepecik Training and Research Hospital 2018-12-31
NCT03883061 Mathematical Modeling and Risk Factor Analysis for Mortality of Sepsis https://ClinicalTrials.gov/show/NCT03883061 Recruiting Shanghai Tongji Hospital, Tongji University School of Medicine 2019-03-01
NCT03789838 Effect of Sepsis Response Team in the Emergency Department https://ClinicalTrials.gov/show/NCT03789838 Completed Oslo University Hospital 2018-05-15
NCT03746743 Severity Index of Neonatal Septicemia Using Score for Neonatal Acute Physiology (SNAP) II https://ClinicalTrials.gov/show/NCT03746743 Completed Cairo University 2018-08-31
NCT03634891 An Audit Study on Management of Neonates With Neonatal Sepsis Admitted to Asyut University Children Hospital https://ClinicalTrials.gov/show/NCT03634891 Recruiting Assiut University 2019-06-01
NCT02312024 International Registry on the Use of the CytoSorb Adsorber https://ClinicalTrials.gov/show/NCT02312024 Recruiting Jena University Hospital 2020-12-31
NCT03523169 Cerebral Oxygen Challenge of Passive Leg Raising Test in Sepsis https://ClinicalTrials.gov/show/NCT03523169 Completed Peking Union Medical College Hospital 2017-11-01
NCT04448951 Immune Homeostasis in Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04448951 Recruiting Charles University, Czech Republic 2021-12-31
NCT02180009 Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis https://ClinicalTrials.gov/show/NCT02180009 Completed Chinese PLA General Hospital 2015-08-31
NCT02936232 Severe Sepsis and Septic Shock Registry https://ClinicalTrials.gov/show/NCT02936232 Recruiting Seoul National University Hospital 2022-03-31
NCT03029039 Platelet-associated Inflammation in Severe Sepsis https://ClinicalTrials.gov/show/NCT03029039 Recruiting Centre Hospitalier Universitaire de Saint Etienne 2020-06-30
NCT03956043 Diagnostic Accuracy in Sepsis https://ClinicalTrials.gov/show/NCT03956043 Recruiting Oslo University Hospital 2021-05-15